Tricyclohexylphosphine oxide

Tricyclohexylphosphine oxide is used as a ligand for a range of metal-catalyzed organic transformations. Ligand used in the Pd-catalyzed coupling of malononitrile with aryl halides.1 Bulky phosphine ligand used with a Pd(0)-triolefinic macrocycle catalyst for Suzuki coupling of aryl bromides and chlorides. This ligand is applied with Ni as a key intermediate in the formation of cylcopentane compounds.

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