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Thermo Scientific Chemicals
Deoxycholic acid, 98.5%
Deoxycholic acid, CAS # 83-44-3, is a bile acid and blood serum metabolite. | CAS: 83-44-3 | C24H40O4 | 392.58 g/mol
化学物質識別子
CAS83-44-3
IUPAC Name(4R)-4-[(1R,3aS,3bR,5aR,7R,9aS,9bS,11S,11aR)-7,11-dihydroxy-9a,11a-dimethyl-hexadecahydro-1H-cyclopenta[a]phenanthren-1-yl]pentanoic acid
Molecular FormulaC24H40O4
InChI KeyKXGVEGMKQFWNSR-LLQZFEROSA-N
SMILES[H][C@@]12CC[C@H]([C@H](C)CCC(O)=O)[C@@]1(C)[C@@H](O)C[C@@]1([H])[C@@]2([H])CC[C@]2([H])C[C@H](O)CC[C@]12C
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仕様
スペックシート
スペックシートLoss on drying=<1 % (140°C, 4 hrs) (under vacuum < 5 mmHg)
Residue after ignition=<0.2 %
Appearance (Form)Crystalline powder
Infrared spectrumConforms
Melting point172°C to 178°C
さらに表示
This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
General Description
• Deoxycholic acid is a 5beta-cholan-24-oic acid derivative with hydroxy substitutions at carbons 3 and 12
• Deoxycholic acid’s role is to absorb fats by emulsifying and solubilizing them
Applications
• Deoxycholic acid may be used for laboratory study of submental fat
• Deoxycholic acid is capable of disrupting cell membranes
• In laboratory research applications, deoxycholic acid can be used to solubilize proteins or as a secondary standard
RUO – Research Use Only
General References:
- Funabashi, M.; Grove, T.L., Wang, M.; Varma, Y.; McFadden, M.E.; Brown, L.C.; Guo, C.; Higginbottom, S.; Almo, S.C.; Fischbach, M.A. A metabolic pathway for bile acid dehydroxylation by the gut microbiome. Nature. 2020, 582(7813), 566-570.
- Peach, M.; Marsh, N.; Macphee, D.J. Protein solubilization: attend to the choice of lysis buffer. Methods Mol Biol. 2012, 869, 37-47.