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Thermo Scientific Chemicals
2-Thiouracil, 99%, Thermo Scientific Chemicals
2-Thiouracil, Thiouracil or 4-Hydroxy-2-mercaptopyrimidine, CAS # 141-90-2, is the modified analog of the nucleotide base, uracil.
化学物質識別子
CAS141-90-2
IUPAC Name2-sulfanylidene-1,2,3,4-tetrahydropyrimidin-4-one
Molecular FormulaC4H4N2OS
InChI KeyZEMGGZBWXRYJHK-UHFFFAOYSA-N
SMILESO=C1NC(=S)NC=C1
さらに表示
仕様
スペックシート
スペックシートHPLC>=98.0 %
Appearance (Color)White to light yellow
Infrared spectrumConforms
Loss on drying=<0.5 % (105°C, 3 h)
Appearance of solution(0.5% in 1M NaOH) Clear to light hazy
さらに表示
This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
General description
• 2-Thiouracil (Thiouracil or 4-Hydroxy-2-mercaptopyrimidine) is a nucleotide analog with a C-2 thioxo substitution
• 2-Thiouracil is a melanocyte suppressor and thyroid inhibitor
Applications
• 2-Thiouracil can be used to inhibit nitric oxide synthase and suppresses nitric oxide signaling in vitro
• 2-Thiouracil can be used for labeling of RNA in vitro
• 2-Thiouracil is intended for research applications only
RUO – Research Use Only
Literature references
Yang, W.; Shen, Z.; Wen, S.; Wang, W.; Hu, M. Mechanisms of multiple neurotransmitters in the effects of Lycopene on brain injury induced by Hyperlipidemia. Lipids Health Dis. 2018, 17(1), 13. Erratum in: Lipids Health Dis. 2018, 17 (1), 65.
Wauters, J.; Van, Meulebroek L.; Fichant, E.; Delahaut, P.; Vanhaecke, L. Discrimination between Synthetically Administered and Endogenous Thiouracil Based on Monitoring of Urine, Muscle, and Thyroid Tissue: An in Vivo Study in Young and Adult Bovines. J Agric Food Chem. 2017, 65(30), 6231-6239.