(+)-Dehydroisoandrosterone, 99%, Thermo Scientific Chemicals

Name: (+)-Dehydroisoandrosterone, 99%, Thermo Scientific Chemicals
SKU: 154980500

(+)-Dehydroisoandrosterone, CAS # 53-43-0, also known as androstenolone, is an endogenous steroid hormone precursor. It is an intermediate in the conversion of cholesterol to androgens and estrogens.

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製品番号（カタログ番号）	数量	パッケージ
154980500	50g	Glass bottle
154980025	2.5g	Glass bottle
154980100	10g	Glass bottle

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製品番号（カタログ番号） 154980500

価格（JPY）

数量:

50g

パッケージ:

Glass bottle

一括またはカスタム形式をリクエストする

化学物質識別子

CAS53-43-0

IUPAC Name(3aS,3bR,7S,9aR,9bS,11aS)-7-hydroxy-9a,11a-dimethyl-1H,2H,3H,3aH,3bH,4H,6H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-one

Molecular FormulaC19H28O2

InChI KeyFMGSKLZLMKYGDP-USOAJAOKSA-N

SMILESC[C@]12CC[C@H]3[C@@H](CC=C4C[C@@H](O)CC[C@]34C)[C@@H]1CCC2=O

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仕様

スペックシート

Appearance (Color)White to off-white

Infrared spectrumConforms

HPLC>=98.5 %

Specific optical rotation+11.0° to +13.0° (20°C, 589 nm) (c=2, Ethanol 96%)

Appearance (Form)Crystalline powder

さらに表示

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

• (+)-Dehydroisoandrosterone is an endogenous steroid hormone precursor that acts as an intermediate in the conversion of cholesterol to androgens and estrogens

Applications

• It is an endogenous and naturally occurring steroid hormone produced largely by the adrenal glands, but also by the testes and ovaries

• It has been described that (+)-Dehydroisoandrosterone could have a role in the immune and stress response

• (+)-Dehydroisoandrosterone can be converted to testosterone, androstenedione, estradiol, and estrone

• (+)-Dehydroisoandrosterone is derived from cholesterol through the action of two cytochrome P450 enzymes

• It can induce both direct and indirect in vivo biological effects, by modulating GABA- α receptor and N-Methyl-D-aspartic acid (NMDA) receptor complexes.

• It can also increase pancreatic β cell insulin secretion and anti-glucocorticoid activity

• It is useful to detect excess adrenal activity since it is produced nearly exclusively by the adrenal glands

RUO – Research Use Only

Literature References

Prough, R.; Clark, B.; Klinge, C. Novel mechanisms for DHEA action. Journal of Molecular Endocrinology, 2016, 56, 3, R139-R155.