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| 製品番号(カタログ番号) | 数量 |
|---|---|
| 164410100 | 10 g |
General Description
• Testosterone is a steroid sex hormone from the androstane family and is important for the maintenance of several biological functions
• This compound is an androgen that exerts its function by binding to and activating the androgen receptor
Applications
• Testosterone is irreversibly converted to dihydrotestosterone (DHT) in target tissues by the enzyme 5-∝ reductase
• Testosterone or DHT (its active metabolite) ligand-androgen receptor complexes act as a transcription factor, stimulating the expression of several responsive genes
• It antagonizes the androgen receptor to induce gene expression that causes the growth, development, and maintenance of several biological functions
• This compound is commonly used in vivo studies as an ester derivative due to its rapid metabolism by the liver
Literature References
Tyagi, V.; Scordo, M.; Yoon, R.; Liporace, F.; Greene, L. Revisiting the role of testosterone: Are we missing something? Rev Urol. 2017, 19 (1), 16–24.