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Thermo Scientific Chemicals
Squalene, 99+%, Thermo Scientific Chemicals
Squalene, CAS # 111-02-4, is a biosynthetic precursor to all steroids and ergosterol and is used as an immunologic adjuvant in vaccines.
化学物質識別子
CAS111-02-4
IUPAC Name(6E,10E,14E,18E)-2,6,10,15,19,23-hexamethyltetracosa-2,6,10,14,18,22-hexaene
Molecular FormulaC30H50
InChI KeyYYGNTYWPHWGJRM-AAJYLUCBSA-N
SMILESCC(C)=CCC\C(C)=C\CC\C(C)=C\CC\C=C(/C)CC\C=C(/C)CCC=C(C)C
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仕様
スペックシート
スペックシートAppearance (Color)Clear colorless to light yellow
GC>=99.0 %
Refractive index1.4945 to 1.4965 (20°C, 589 nm)
Density(20°C) 0.845 to 0.865 g/ml
Iodine value360 to 400 g I2/100 g
さらに表示
This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
General description
• Squalene is a precursor to steroids and ergosterols
• It can be used in preparation of lipids, steroids, and fat-soluble vitamins
Applications
• Squalene is used as an immunologic adjuvant in vaccines
• It plays a vital role in the preparation of cholesterol, steroid hormones, and vitamin D
• It can also serve as a lubricant for fatty acid surfactant films adsorbed on iron oxide surfaces
RUO – Research Use Only
General References:
- Sánchez-Fidalgo, S.; Villegas, I.; Rosillo, M. Á.; Aparicio-Soto, M.; de la Lastra, C. A. Dietary squalene supplementation improves DSS-induced acute colitis by downregulating p38 MAPK and NFkB signaling pathways. Mol. Nutr. Food Res. 2015, 59 (2), 284-292.
- Kedl, J. D.; Kedl, R. M. How squalene GLAdly helps generate antigen-specific T cells via antigen-carrying neutrophils and IL-18. Eur. J. Immunol. 2015, 45 (2), 376-379.