AMAS (N-α-maleimidoacet-oxysuccinimide ester)
AMAS (N-α-maleimidoacet-oxysuccinimide ester)
Citations & References (4)
Thermo Scientific™

AMAS (N-α-maleimidoacet-oxysuccinimide ester)

Thermo Scientific Pierce AMASは、非常に短いスペーサーアーム（4.4オングストローム）の両端にNHSエステル基およびマレイミド反応基を含む、アミン基-スルフヒドリル基間架橋剤です。AMASの特徴：•反応基：NHSエステルおよびマレイミド• 反応対象：アミノ基およびスルフヒドリル基•詳細を見る
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製品番号（カタログ番号）数量
2229550 mg
製品番号（カタログ番号） 22295
価格（JPY）
36,700
Each
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数量:
50 mg
一括またはカスタム形式をリクエストする
Thermo Scientific Pierce AMASは、非常に短いスペーサーアーム（4.4オングストローム）の両端にNHSエステル基およびマレイミド反応基を含む、アミン基-スルフヒドリル基間架橋剤です。

AMASの特徴：

•反応基：NHSエステルおよびマレイミド
• 反応対象：アミノ基およびスルフヒドリル基
• AMAS、BMPS、GMBSおよびEMCSを含むもっとも短い脂肪族スペーサーシリーズ
• NHSエステルの末端はpH 7～9で第一級アミンと結合し安定したアミド結合を形成
• マレイミドはpH 6.5～7.5で-SH基と反応し、安定したチオエーテル結合を形成
• 非切断性
• 不水溶性（DMFまたはDMSOで最初に溶解）
• 非常に短い脂肪族スペーサーは免疫応答を誘発する可能性が低い
研究用途にのみご使用ください。診断目的には使用できません。
仕様
細胞透過性Yes
概要AMAS
形状Powder
標識法化学的標識
分子量252.18
PEG化No
製品ラインPierce
数量50 mg
反応性部分マレイミド、NHSエステル
出荷条件Ambient
溶解性DMF、DMSO
スペーサーアーム長4.4 Å
水溶性No
化学反応性Amine-Sulfhydryl
CleavableNo
クロスリンカータイプヘテロ三官能性
フォーマットStandard
製品タイプ架橋剤
スペーサー短鎖
Unit SizeEach
組成および保存条件
4℃で乾燥した場所に保存。

よくあるご質問（FAQ）

Can you provide the shelf-life for AMAS (N-α-maleimidoacet-oxysuccinimide ester)?

AMAS (N-α-maleimidoacet-oxysuccinimide ester is covered under our general 1-year warranty and is guaranteed to be fully functional for 12 months from the date of shipment, if stored as recommended. Please see section 8.1 of our Terms & Conditions of Sale (https://www.thermofisher.com/content/dam/LifeTech/Documents/PDFs/Terms-and-Conditions-of-Sale.pdf) for more details.

Find additional tips, troubleshooting help, and resources within our Protein Purification and Isolation Support Center.

引用および参考文献 (4)

引用および参考文献
Abstract
Dual binding mode of the nascent polypeptide-associated complex reveals a novel universal adapter site on the ribosome.
Authors:Pech M, Spreter T, Beckmann R, Beatrix B
Journal:J Biol Chem
PubMed ID:20410297
'Nascent polypeptide-associated complex (NAC) was identified in eukaryotes as the first cytosolic factor that contacts the nascent polypeptide chain emerging from the ribosome. NAC is present as a homodimer in archaea and as a highly conserved heterodimer in eukaryotes. Mutations in NAC cause severe embryonically lethal phenotypes in mice, Drosophila ... More
Analysis of RovA, a transcriptional regulator of Yersinia pseudotuberculosis virulence that acts through antirepression and direct transcriptional activation.
Authors:Tran HJ, Heroven AK, Winkler L, Spreter T, Beatrix B, Dersch P
Journal:J Biol Chem
PubMed ID:16257976
'The transcription factor RovA of Yersinia pseudotuberculosis and analogous proteins in other Enterobacteriaceae activate the expression of virulence genes that play a crucial role in stress adaptation and pathogenesis. In this study, we demonstrate that the RovA protein forms dimers independent of DNA binding, stimulates RNA polymerase, most likely via ... More
A central role for the T1 domain in voltage-gated potassium channel formation and function.
Authors:Strang C, Cushman SJ, DeRubeis D, Peterson D, Pfaffinger PJ
Journal:J Biol Chem
PubMed ID:11312262
To interpret the recent atomic structures of the Kv (voltage-dependent potassium) channel T1 domain in a functional context, we must understand both how the T1 domain is integrated into the full-length functional channel protein and what functional roles the T1 domain governs. The T1 domain clearly plays a role in ... More
Spatial and dynamic interactions between phospholamban and the canine cardiac Ca2+ pump revealed with use of heterobifunctional cross-linking agents.
Authors:Chen Z, Stokes DL, Rice WJ, Jones LR
Journal:J Biol Chem
PubMed ID:12972413
Heterobifunctional thiol to amine cross-linking agents were used to gain new insights on the dynamics and conformational factors governing the interaction between the cardiac Ca2+ pump (SERCA2a) and phospholamban (PLB). PLB is a small protein inhibitor of SERCA2a that reduces enzyme affinity for Ca2+ and thereby regulates cardiac contractility. We ... More