SIAB (succinimidyl (4-iodoacetyl)aminobenzoate)

Citations & References (5)

Thermo Scientific™

SIAB (succinimidyl (4-iodoacetyl)aminobenzoate)

Thermo Scientific Pierce SIABは、中程度の長さ（10.6オングストローム）の架橋剤で、N-ヒドロキシスクシンイミド（NHS）エステルおよびヨードアセチル反応基を介してアミン基-スルフヒドリル基を結合させます詳細を見る

製品番号（カタログ番号）	数量
22329	50 mg

製品番号（カタログ番号） 22329

価格（JPY）

45,900

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Ends: 26-Dec-2025

76,500

割引額 30,600 (40%)

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50 mg

Thermo Scientific Pierce SIABは、中程度の長さ（10.6オングストローム）の架橋剤で、N-ヒドロキシスクシンイミド（NHS）エステルおよびヨードアセチル反応基を介してアミン基-スルフヒドリル基を結合させます。

SIABの特徴：

•反応基：NHSエステルとヨードアセチル
• 以下と反応：アミノ基およびスルフヒドリル基
• 非切断性
• 不水溶性（DMFまたはDMSOで最初に溶解）。Sulfo-SIABとの比較
• 安定した酵素-IgGコンジュゲートの調製に使用
•製品リファレンス：
架橋剤アプリケーションガイド - この製品に関する最近の文献参照情報を検索

関連製品
Sulfo-SIAB (sulfosuccinimidyl (4-iodoacetyl)aminobenzoate)

研究用途にのみご使用ください。診断目的には使用できません。

細胞透過性Yes

概要SIAB

形状Powder

標識法化学的標識

分子量402.14

PEG化No

製品ラインPierce

数量50 mg

反応性部分ハロアセチル、NHSエステル

出荷条件Ambient

溶解性DMF、DMSO

スペーサーアーム長10.6 Å

水溶性No

化学反応性Amine-Sulfhydryl

CleavableNo

クロスリンカータイプヘテロ三官能性

フォーマットStandard

製品タイプ架橋剤

スペーサー中程度の長さ

Unit SizeEach

組成および保存条件

Sulfo-SIABは受領後、遮光された-20℃の乾燥した状態で保存します。試薬は室温で出荷されます。

よくあるご質問（FAQ）

Can you provide the shelf-life for SIAB (succinimidyl (4-iodoacetyl)aminobenzoate)?

SIAB (succinimidyl (4-iodoacetyl)aminobenzoate) is covered under our general 1-year warranty and is guaranteed to be fully functional for 12 months from the date of shipment, if stored as recommended. Please see section 8.1 of our Terms & Conditions of Sale (https://www.thermofisher.com/content/dam/LifeTech/Documents/PDFs/Terms-and-Conditions-of-Sale.pdf) for more details.

Find additional tips, troubleshooting help, and resources within our Protein Purification and Isolation Support Center.

引用および参考文献 (5)

引用および参考文献

Abstract

Chip-based genotyping by mass spectrometry.

Authors:Tang K, Fu DJ, Julien D, Braun A, Cantor CR, KÃ¶ster H

Journal:Proc Natl Acad Sci U S A

PubMed ID:10468554

Silicon chips with immobilized target DNAs were used for accurate genotyping by mass spectrometry. Genomic DNAs were amplified with PCR, and the amplified products were covalently attached to chip wells via N-succinimidyl (4-iodoacetyl)aminobenzoate (SIAB) chemistry. Primer annealing, extension, and termination were performed on a 1-microl scale directly in the chip ... More

Covalent attachment of synthetic DNA to self-assembled monolayer films.

Authors:Chrisey LA, Lee GU, O'Ferrall CE

Journal:Nucleic Acids Res

PubMed ID:8760890

'The covalent attachment of thiol-modified DNA oligomers; to self-assembled monolayer silane films on fused silica and oxidized silicon substrates is described. A heterobifunctional crosslinking molecule bearing both thiol- and amino-reactive moieties was used to tether a DNA oligomer (modified at its terminus with a thiol group) to an aminosilane film ... More

Gbeta subunit interacts with a peptide encoding region 956-982 of adenylyl cyclase 2. Cross-linking of the peptide to free Gbetagamma but not the heterotrimer.

Authors:Weng G, Li J, Dingus J, Hildebrandt JD, Weinstein H, Iyengar R

Journal:J Biol Chem

PubMed ID:8900107

The region encoded by amino acids 956-982 of adenylyl cyclase 2 is important for Gbetagamma stimulation. Interactions of a peptide encoding the 956-982 region of adenylyl cyclase 2 (QEHAQEPERQYMHIGTMVEFAYALVGK (QEHA peptide)) with Gbetagamma subunits were studied. QEHA peptide was covalently attached to beta subunit of free Gbetagamma by the cross-linker ... More

Mitochondrial protein import: recognition of internal import signals of BCS1 by the TOM complex.

Authors:Stan T, Brix J, Schneider-Mergener J, Pfanner N, Neupert W, Rapaport D

Journal:Mol Cell Biol

PubMed ID:12640110

BCS1, a component of the inner membrane of mitochondria, belongs to the group of proteins with internal, noncleavable import signals. Import and intramitochondrial sorting of BCS1 are encoded in the N-terminal 126 amino acid residues. Three sequence elements were identified in this region, namely, the transmembrane domain (amino acid residues ... More

Use of immobilized PCR primers to generate covalently immobilized DNAs for in vitro transcription/translation reactions.

Authors:Andreadis JD, Chrisey LA

Journal:Nucleic Acids Res

PubMed ID:10606673

We have developed a novel biochemical method to simultaneously amplify and immobilize a target gene onto insoluble particles using PCR. This method employs the covalent attachment of one of two PCR primers to a particle surface either directly during DNA synthesis of the primer or post-DNA synthesis, through the use ... More