Search

  • お問い合わせ一覧​
  • クイックオーダー
Paclitaxel, 99+%
元素の検索元素の検索構造の検索構造の検索
Paclitaxel, 99+%
Paclitaxel, 99+%
Paclitaxel, 99+%
Thermo Scientific Chemicals

Paclitaxel, 99+%

Paclitaxel, also known as Taxol, CAS # 33069-62-4 is a chemotherapeutic drug that acts through stabilizing microtubule assembly and arresting cell cycle progression. | CAS: 33069-62-4 | C47H51NO14 | 853.92 g/mol
テクニカルサポートオーダーサポート
表示を変更buttonViewtableView
数量:
1 mg
5 mg
25 mg
ChemDexChem dexTM Webアプリをお試しください
製品番号（カタログ番号） 328420250
価格（JPY）
-
見積もりを依頼する
数量:
25 mg
一括またはカスタム形式をリクエストする
化学物質識別子
CAS33069-62-4
IUPAC Name(1S,2S,4S,7R,9S,10S,12R,15S)-4,12-bis(acetyloxy)-1,9-dihydroxy-15-{[(2R,3S)-2-hydroxy-3-phenyl-3-(phenylformamido)propanoyl]oxy}-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.0³,¹⁰.0⁴,⁷]heptadec-13-en-2-yl benzoate
Molecular FormulaC47H51NO14
InChI KeyRCINICONZNJXQF-VAZQATRQSA-N
SMILESCC(=O)O[C@@H]1C2=C(C)[C@H](C[C@@](O)([C@@H](OC(=O)C3=CC=CC=C3)C3[C@@]4(CO[C@@H]4C[C@H](O)[C@@]3(C)C1=O)OC(C)=O)C2(C)C)OC(=O)[C@H](O)[C@@H](NC(=O)C1=CC=CC=C1)C1=CC=CC=C1
さらに表示
仕様Specification Sheetスペックシート
Appearance (Color)White
Appearance (Form)Powder
Infrared spectrumConforms
Melting point203°C to 223°C
HPLC>=99.0 %
This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

  • Paclitaxel is a naturally ocurring compound originally isolated from the tree T. brevifolia
  • Paclitaxel binds tubulin and stabilizes microtubule formation, preventing disassembly
  • Paclitaxel is used as a drug to arrest cells at the mitotic checkpoint and block cell cycle progression, thus inducing death of cancer cells

Applications

  • Paclitaxel can be used in preclinical laboratory research on diseases such as cancer, heart disease, inflammatory disorders, and hepatic fibrosis
  • Paclitaxel can be used as a tool in cell biology to study mitotic checkpoint arrest conditions and downstream signaling cascades
RUO – Research Use Only

General References:

  1. Zhu, L.; Chen, L. Progress in research on paclitaxel and tumor immunotherapy. Cell Mol Biol Lett. 2019, 24, 40.
  2. Zhang, D.; Yang, R.; Wang, S.; Dong, Z. Paclitaxel: new uses for an old drug. Drug Des Devel Ther. 2014, 8, 279-84.
  3. Weaver, B.A. How Taxol/paclitaxel kills cancer cells. Mol Biol Cell. 2014, 25(18), 2677-81.