GlutaMAX™ Supplement

Try new Pen-Strep antibiotic with GlutaMAX supplement, a stable alternative to L-glutamine that enhances cell health. Learn more >

Citations & References (4)

Gibco™

GlutaMAX™ Supplement

Name: GlutaMAX™ Supplement
SKU: 35050079

多くの細胞に適用できるL-グルタミン。 GlutaMAX™-Iサプリメントは、細胞代謝のみにより培地から除去されます。分解による毒性代謝産物の蓄積はありません。0.85% NaClで200 mM提供されます。詳細を見る

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製品番号（カタログ番号）	数量
35050079	20 x 100 mL
35050061	100 mL

2 オプション

製品番号（カタログ番号） 35050079

価格（JPY）

194,600

Each

お問い合わせください ›

数量:

20 x 100 mL

多くの細胞に適用できるL-グルタミン。 GlutaMAX™-Iサプリメントは、細胞代謝のみにより培地から除去されます。分解による毒性代謝産物の蓄積はありません。

0.85% NaClで200 mM提供されます。水溶液では極めて安定しています。

ジペプチドL-Alanyl-L-グルタミンが含まれています。

用途:
体外診断（IVD）

仕様

細胞タイプMammalian Cells

濃度100 X

培養タイプMammalian Cell Culture

使用対象（アプリケーション）Clinical Research, Translational Research

グリーン機能Sustainable packaging

製造品質cGMP-compliant under the ISO 13485 standard

浸透圧440 - 500 mOsm/kg

製品ラインGibco, GlutaMAX

数量20 x 100 mL

品質保持期間24 Months

電子線源Animal origin-free

分類Animal Origin-free

形状Liquid

製品タイプGlutaMax

無菌性Sterile-filtered

pH4.7 to 6

Unit SizeEach

組成および保存条件

Storage conditions: 15°C to 30°C
Alternate storage conditions: -5°C to -20°C and 2°C to 8°C
Shipping conditions: Room temperature
Shelf life: 24 months from date of manufacture

よくあるご質問（FAQ）

Why is GlutaMAX Supplement (Cat. Nos. 35050061, 35050079) recommended over L-glutamine when reconstituting Geltrex Reduced Growth Factor Basement Membrane Matrix?

GlutaMAX Supplement (Cat. No. 35050061, 35050079) is highly recommended to reconstitute Geltrex Reduced Growth Factor Basement Membrane Matrix because it offers higher stability than L-glutamine. The L-glutamine in Geltrex matrix comes in the form of the dipeptide L-alanyl-L-glutamine, which degrades slower than L-glutamine in cell culture. While GlutaMAX supplement is highly recommended, it is not required for Geltrex matrix–based culture systems.

Find additional tips, troubleshooting help, and resources within our Cell Culture Support Center.

Does Dynamis AGT Medium (Cat. Nos. A2617501, A2617502, A2617503, A2617504) require supplementation for use?

When using Dynamis AGT Medium (Cat. Nos. A2617501, A2617502, A2617503, A2617504) for culturing a CHO cell line other than the glutamine synthetase (GS) gene expression system (GS-CHO expression system), the addition of 2-8 mM L-glutamine or a similar amount of GlutaMAX Supplement (Cat. No. 35050079, 35050061) is recommended.

Note: We recommend that you supplement with glucose as needed so that glucose levels don’t fall below 2g/L in culture (see the product User Guide for more details).

Find additional tips, troubleshooting help, and resources within our Cell Culture Support Center.

Do my cells need to adapt to GlutaMAX Supplement (Cat. No. 35050061, 35050079)?

Some cell lines may require an adaptation period, and the culture may lag in growth until it becomes accustomed to GlutaMAX Supplement (Cat. No. 3050061, 35050079). For serum-free media it is best to add L-glutamine along with GlutaMAX supplement. We don’t recommend that you use GlutaMAX supplement with insect cells such as Sf9.

Find additional tips, troubleshooting help, and resources within our Cell Culture Support Center.

Will depletion, absence, or breakdown of essential growth-promoting components such as glutamine or growth factors reduce the growth rate of my culture?

Yes. If you suspect that this is the case, remove the medium and add fresh medium. Alternatively, you can supplement medium with growth-promoting components. It is also possible to substitute GlutaMax I or II for glutamine in the medium to prevent glutamine exhaustion.

Find additional tips, troubleshooting help, and resources within our Cell Culture Support Center.

Will the media formulations containing GlutaMAX supplement change with respect to L-glutamine content?

In all media containing GlutaMAX supplement dipeptides as a substitute for L-glutamine, concentration is equimolar with the L-glutamine in the original formulation.

Find additional tips, troubleshooting help, and resources within our Cell Culture Support Center.

View all GlutaMAX™ Supplement FAQs

引用および参考文献 (4)

引用および参考文献

Abstract

Directed differentiation of pancreatic δ cells from human pluripotent stem cells.

Authors:Chen L,Wang N,Zhang T,Zhang F,Zhang W,Meng H,Chen J,Liao Z,Xu X,Ma Z,Xu T,Liu H

Journal:Nature communications

PubMed ID:39068220

Dysfunction of pancreatic Î´ cells contributes to the etiology of diabetes. Despite their important role, human Î´ cells are scarce, limiting physiological studies and drug discovery targeting Î´ cells. To date, no directed Î´-cell differentiation method has been established. Here, we demonstrate that fibroblast growth factor (FGF) 7 promotes pancreatic ... More

Production, concentration and titration of pseudotyped HIV-1-based lentiviral vectors.

Authors:Kutner RH, Zhang XY, Reiser J,

Journal:Nat Protoc

PubMed ID:19300443

'Over the past decade, lentiviral vectors have emerged as powerful tools for transgene delivery. The use of lentiviral vectors has become commonplace and applications in the fields of neuroscience, hematology, developmental biology, stem cell biology and transgenesis are rapidly emerging. Also, lentiviral vectors are at present being explored in the ... More

IDH mutation impairs histone demethylation and results in a block to cell differentiation.

Authors:Lu C, Ward PS, Kapoor GS, Rohle D, Turcan S, Abdel-Wahab O, Edwards CR, Khanin R, Figueroa ME, Melnick A, Wellen KE, O'Rourke DM, Berger SL, Chan TA, Levine RL, Mellinghoff IK, Thompson CB,

Journal:Nature

PubMed ID:22343901

Recurrent mutations in isocitrate dehydrogenase 1 (IDH1) and IDH2 have been identified in gliomas, acute myeloid leukaemias (AML) and chondrosarcomas, and share a novel enzymatic property of producing 2-hydroxyglutarate (2HG) from a-ketoglutarate. Here we report that 2HG-producing IDH mutants can prevent the histone demethylation that is required for lineage-specific progenitor ... More

Characterization of pluripotent stem cells.

Authors:Martí M, Mulero L, Pardo C, Morera C, Carrió M, Laricchia-Robbio L, Esteban CR, Izpisua Belmonte JC,

Journal:Nat Protoc

PubMed ID:23306458

Characterization of pluripotent stem cells is required for the registration of stem cell lines and allows for an impartial and objective comparison of the results obtained when generating multiple lines. It is therefore crucial to establish specific, fast and reliable protocols to detect the hallmarks of pluripotency. Such protocols should ... More