Ciprofloxacin, 98%

Ciprofloxacin, CAS# 85721-33-1, is a second-generation fluoroquinolone showing antibiotic activity commonly used against susceptible organisms mainly gram-negative bacteria.

製品番号（カタログ番号）	数量	パッケージ
449620250	25g	Glass Bottle

製品番号（カタログ番号） 449620250

価格（JPY）

パッケージ:

Glass Bottle

一括またはカスタム形式をリクエストする

化学物質識別子

CAS85721-33-1

IUPAC Name1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid

Molecular FormulaC17H18FN3O3

InChI KeyMYSWGUAQZAJSOK-UHFFFAOYSA-N

SMILESOC(=O)C1=CN(C2CC2)C2=CC(N3CCNCC3)=C(F)C=C2C1=O

さらに表示

Appearance (Color)White to light yellow

HPLC>=97.5 %

Sulfated ash=<0.1 %

Appearance (Form)Crystalline powder

Loss on drying=<1 %

さらに表示

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Information

• Ciprofloxacin is considered a synthetic broad-spectrum second-generation compound with antibiotic activity mainly against gram-negative bacteria
• It inhibits bacterial DNA gyrase and topoisomerase IV, enzymes that are essential for DNA replication, cell division, and causes double-strand breaks in the bacterial chromosome

Applications

• Ciprofloxacin presents more activity against gram-negative bacteria than gram-positive bacteria.
• Ciprofloxacin does not present cross-resistance between fluoroquinolones and other antibiotics classes, which is beneficial in laboratory experiments when other antibiotics are no longer effective

RUO – Research Use Only

Literature References

Nix, D. E.; DeVito, J. M. Ciprofloxacin and norfloxacin, two fluoroquinolone antimicrobials. Clin Pharm. 1987, 6, (2), 105-17.

Sen, et al. Anxiogenic potential of ciprofloxacin and norfloxacin in rats. Singapore Med. J. 2007, 48, (11), 1028-30.