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Thermo Scientific Chemicals
Flurbiprofen, 98%
Flurbiprofen, CAS # 5104-49-4, is a monocarboxylic acid-based nonsteroidal anti-inflammatory (NSAID).
化学物質識別子
CAS5104-49-4
IUPAC Name2-{2-fluoro-[1,1'-biphenyl]-4-yl}propanoic acid
Molecular FormulaC15H13FO2
InChI KeySYTBZMRGLBWNTM-UHFFFAOYNA-N
SMILESCC(C(O)=O)C1=CC=C(C(F)=C1)C1=CC=CC=C1
さらに表示
仕様
スペックシート
スペックシートInfrared spectrumConforms
Appearance (Form)Powder
Melting point110°C to 116°C
HPLC>=97.5 %
Appearance (Color)White to off-white
This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
General Description
• Flurbiprofen is composed of a 2-fluoro-[1,1'-biphenyl-4-yl] moiety attached to propionic acid
• Flurbiprofen works by inhibiting prostaglandin-endoperoxide synthase and reducing the production of prostaglandins and pyrogens
Applications
• Flurbiprofen is useful for studying pathways associated with prostaglandin production
• It is suitable for laboratory research on pain, inflammation, ocular pressure, and postoperative recovery
RUO – Research Use Only
Literature References
Sun, M.; Cong, X.; Chang, E.; Miao, M.; Zhang, J. Efficacy of Flurbiprofen for Postoperative Pain in Chinese Surgical Patients: A Meta-Analysis. J Surg Res. 2020, 252:80-88.
Caban-Toktas, S.; Sahin, A.; Lule, S.; Esendagli, G.; Vural, I.; Karlı Oguz, K.; Soylemezoglu, F.; Mut, M.; Dalkara, T.; Khan, M.; Capan, Y. Combination of Paclitaxel and R-flurbiprofen loaded PLGA nanoparticles suppresses glioblastoma growth on systemic administration. Int J Pharm. 2020, 578,119076.