Streptomycin sulfate

Streptomycin sulfate, CAS # 3810-74-0, is the sulfate salt form of streptomycin, and an aminoglycoside with antibacterial activity. It also shows a protein synthesis inhibitory activity.

製品番号（カタログ番号）	数量
455341000	100 g

製品番号（カタログ番号） 455341000

価格（JPY）

見積もりを依頼する

100 g

一括またはカスタム形式をリクエストする

化学物質識別子

CAS3810-74-0

IUPAC Namebis(N''-[(1R,2R,3S,4R,5R,6S)-3-[(diaminomethylidene)amino]-4-{[(2R,3R,4R,5S)-3-{[(2S,3S,4S,5R,6S)-4,5-dihydroxy-6-(hydroxymethyl)-3-(methylamino)oxan-2-yl]oxy}-4-formyl-4-hydroxy-5-methyloxolan-2-yl]oxy}-2,5,6-trihydroxycyclohexyl]guanidine); tris(sulfuric acid)

Molecular FormulaC42H84N14O36S3

InChI KeyQTENRWWVYAAPBI-YCRXJPFRSA-N

SMILESOS(O)(=O)=O.OS(O)(=O)=O.OS(O)(=O)=O.CN[C@H]1[C@H](O)[C@@H](O)[C@H](CO)O[C@H]1O[C@H]1[C@H](O[C@H]2[C@H](O)[C@@H](O)[C@H](N=C(N)N)[C@@H](O)[C@@H]2N=C(N)N)O[C@@H](C)[C@]1(O)C=O.CN[C@H]1[C@H](O)[C@@H](O)[C@H](CO)O[C@H]1O[C@H]1[C@H](O[C@H]2[C@H](O)[C@@H](O)[C@H](N=C(N)N)[C@@H](O)[C@@H]2N=C(N)N)O[C@@H](C)[C@]1(O)C=O

さらに表示

Appearance (Color)White to off-white

Appearance (Form)Powder

Sulfate (SO4)18.0 to 21.5

Loss on drying=<7 %

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

• Streptomycin sulfate is an aminoglycoside sulfate salt derived from Streptomyces griseus that shows antibacterial activity.

• It inhibits initiation and causes misreading of rRNA in protein synthesis. This compound binds to the S12 protein of the bacterial 30S ribosomal subunit, thereby inhibiting peptide elongation and protein synthesis.

Application

• Streptomycin sulfate can be used to study the mechanisms of streptomycin resistance

• This compound can be used in laboratory applications combined with penicillin to inhibit bacterial contamination in in vitro cell culture

• Streptomycin sulfate shows antibiotic activity against Mycobacterium tuberculosis

• This compound can be used as a protein synthesis inhibitor

• It acts against gram-negative and gram-positive bacteria • Streptomycin sulfate also shows a fungicide activity

• It can be used to remove nucleic acids from a biological extract

RUO – Research Use Only

General References:

Kou, Q. Y.; Li, J.; Zhao, B.; Wu, Z. L. Recovery of streptomycin sulfate from the wastewater using foam fractionation coupled with adsorption separation for reusing sodium dodecyl sulfate. J. Chem. Technol. Biotechnol. 2015, 90 (5), 874-879.
Evans, J. F.; Salvador, V.; George, S.; Trevino-Gutierrez, C.; Nunez, C. Mouse aorta-derived mesenchymal progenitor cells contribute to and enhance the immune response of macrophage cells under inflammatory conditions. Stem Cell Res. Ther. 2015, 6 (56), 1-15.