Ceftriaxone sodium salt hemiheptahydrate

Name: Ceftriaxone sodium salt hemiheptahydrate
SKU: 455420010

Ceftriaxone, CAS # 104376-79-6, sodium salt hemiheptahydrate is the sodium salt of ceftriaxone, a third-generation beta-lactam antibiotic of the cephalosporin class.

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製品番号（カタログ番号）	数量
455420010	1 g
455420050	5 g
455420250	25 g

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製品番号（カタログ番号） 455420010

価格（JPY）

見積もりを依頼する

数量:

1 g

一括またはカスタム形式をリクエストする

化学物質識別子

CAS104376-79-6

IUPAC Nametetrasodium 3-({[(6R,7R)-7-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-2-carboxylato-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl}sulfanyl)-2-methyl-5,6-dioxo-1,2,5,6-tetrahydro-1,2,4-triazin-1-ide (6R,7R)-7-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-3-{[(2-methyl-6-oxido-5-oxo-2,5-dihydro-1,2,4-triazin-3-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate heptahydrate

Molecular FormulaC36H46N16Na4O21S6

InChI KeyRGDBKADCOSIOEV-MAODNAKNSA-J

SMILESO.O.O.O.O.O.O.[Na+].[Na+].[Na+].[Na+].CO\N=C(/C(=O)N[C@H]1[C@H]2SCC(CSC3=NC(=O)C(=O)[N-]N3C)=C(N2C1=O)C([O-])=O)C1=CSC(N)=N1.CO\N=C(/C(=O)N[C@H]1[C@H]2SCC(CSC3=NC(=O)C([O-])=NN3C)=C(N2C1=O)C([O-])=O)C1=CSC(N)=N1

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仕様

スペックシート

Water=<10 %

Appearance (Color)White to light yellow

Infrared spectrumConforms

Appearance (Form)Crystalline powder

HPLC>=94 %

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

• Ceftriaxone is the sodium salt of ceftriaxone, a beta-lactam antibiotic of the cephalosporin class that works by inactivating penicillin-binding proteins

Applications

• Penicillin-binding protein inactivation inhibits peptidoglycan cross-linkage and leads to destruction of the cell wall and subsequent lysis

• It exhibits antibiotic activity against gram-negative bacteria

RUO – Research Use Only

Literature References

Grégoire, M.; Dailly, E.; Le Turnier, P.; Garot, D.; Guimard, T.; Bernard, L.; Tattevin, P.; Vandamme, Y.M.; Hoff, J.; Lemaitre, F.; Verdier, M.C.; Deslandes, G.; Bellouard, R.; Sébille, V.; Chiffoleau, A.; Boutoille, D.; Navas, D.; Asseray, N. High-Dose Ceftriaxone for Bacterial Meningitis and Optimization of Administration Scheme Based on Nomogram. Antimicrob Agents Chemother. 2019, 63(9), e00634-19.

Ross, J.D.C.; Brittain, C.; Cole, M.; Dewsnap, C.; Harding, J.; Hepburn, T.; Jackson, L.; Keogh, M.; Lawrence, T.; Montgomery, A.A.; Roberts, T.E.; Sprange, K.; Tan, W.; Thandi S, White J.; Wilson, J.; Duley, L. G-ToG trial team. Gentamicin compared with ceftriaxone for the treatment of gonorrhoea (G-ToG): a randomised non-inferiority trial. Lancet. 2019, 22, 393(10190), 2511-2520. Erratum in: Lancet. 2019, Erratum in: Lancet, 394(10205), 1230.