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Thermo Scientific Chemicals
Lopinavir, 98%, Thermo Scientific Chemicals
Lopinavir, CAS # 192725-17-0, is an antiretroviral drug of the amphetamine class.
化学物質識別子
CAS192725-17-0
IUPAC Name(2S)-N-[(2S,4S,5S)-5-[2-(2,6-dimethylphenoxy)acetamido]-4-hydroxy-1,6-diphenylhexan-2-yl]-3-methyl-2-(2-oxo-1,3-diazinan-1-yl)butanamide
Molecular FormulaC37H48N4O5
InChI KeyKJHKTHWMRKYKJE-SUGCFTRWSA-N
SMILESCC(C)[C@H](N1CCCNC1=O)C(=O)N[C@H](C[C@H](O)[C@H](CC1=CC=CC=C1)NC(=O)COC1=C(C)C=CC=C1C)CC1=CC=CC=C1
さらに表示
仕様
スペックシート
スペックシートAppearance (Color)White to beige
Water=<4 %
HPLC>=97.5 %
Specific optical rotation(On anhydrous substance)
Appearance (Form)Powder
さらに表示
This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
General Description
• Lopinavir is a retroviral protease inhibitor that acts as an antiretroviral and can prevent the propagation of human immunodeficiency virus (HIV) and hepatitis viruses within cells
• Lopinavir is a dicarboxylic acid diamide and a substituted form of amphetamine
Applications
• Lopinavir may be used in the laboratory study of other retroviruses
• Lopinavir is suitable for laboratory research of drug delivery systems; some studies have shown that the activity of lopinavir can be enhanced by alternative delivery methods such as microencapsulation
RUO – Research Use Only
Literature References
Hosseini, F.S.; Malektojari, A.; Ghazizadeh, S.; Hassaniazad, M.; Davoodian, P.; Dadvand, H.; Nikpoor, A.R.; Nikoofal-Sahlabadi, S.; Kahoori, S.; Sepandi, M.; Hassanipour, S.; Fathalipour, M. The efficacy and safety of Ivermectin in patients with mild and moderate COVID-19: A structured summary of a study protocol for a randomized controlled trial. Trials. 2021, 22(1),4. Ansari, H.; Singh, P. Formulation and in-vivo Evaluation of Novel Topical Gel of Lopinavir for Targeting HIV. Curr HIV Res. 2018, 16(4), 270-279.