Ciprofloxacin hydrochloride hydrate, 98%

Ciprofloxacin hydrochloride hydrate, CAS # 128074-72-6, is the hydrate form of the hydrochloride salt of ciprofloxacin, a broad-spectrum antibiotic.

製品番号（カタログ番号）	数量
456880250	25 g

製品番号（カタログ番号） 456880250

価格（JPY）

一括またはカスタム形式をリクエストする

化学物質識別子

CAS128074-72-6

IUPAC Name1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid hydrochloride

Molecular FormulaC17H19ClFN3O3

InChI KeyDIOIOSKKIYDRIQ-UHFFFAOYSA-N

SMILESCl.OC(=O)C1=CN(C2CC2)C2=CC(N3CCNCC3)=C(F)C=C2C1=O

さらに表示

HPLC>=97.5 %

Water4.0 to 7.0 %

Residue after ignition=<0.1 %

Infrared spectrumConforms

Appearance (Color)White to light yellow

さらに表示

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

• Ciprofloxacin HCl is a fluoroquinolone antibiotic that works by binding to bacterial DNA gyrase/DNA topoisomerase, thus inhibiting DNA replication and subsequent bacterial cell division

• It can cause double-stranded breaks in the bacterial chromosome

• Ciprofloxacin HCl is an analog of the antibiotic nalidixic acid

• Works as an antibiotic against both gram-positive and gram-negative bacteria and can have fungicidal activity

Applications

• Used for elimination of mycoplasma in cell culture

• Can be used to study antimicrobial activity and resistance in laboratory settings

RUO – Research Use Only

Literature references

Schmitt, K.; Däubener, W.; Bitter-Suermann, D.; Hadding, U. A safe and efficient method for elimination of cell culture mycoplasmas using ciprofloxacin. J Immunol Methods. 1988, 109(1), 17-25.

Jomehzadeh, N.; Saki, M.; Ahmadi, K.; Zandi, G. The prevalence of plasmid-mediated quinolone resistance genes among Escherichia coli strains isolated from urinary tract infections in southwest Iran. Mol Biol Rep. 2022.

D.C. Hooper, et al. Mechanisms of action of and resistance to ciprofloxacin. Am. J. Med. 1987, 82, (4A), 12-20.