Thermo Scientific Chemicals

2,2,2-Trifluoroethanol, 99+%, Thermo Scientific Chemicals

製品番号(カタログ番号): A10788.22
100 g, Each
Thermo Scientific Chemicals

2,2,2-Trifluoroethanol, 99+%, Thermo Scientific Chemicals

製品番号(カタログ番号): A10788.22
100 g, Each
数量
製品番号(カタログ番号): A10788.22
または、製品番号A10788-22

化学物質識別子

CAS
75-89-8
IUPAC Name
2,2,2-trifluoroethan-1-ol
Molecular Formula
C2H3F3O
InChI Key
RHQDFWAXVIIEBN-UHFFFAOYSA-N
SMILES
OCC(F)(F)F
Appearance (Color)
Clear colorless
Form
Liquid
Assay (GC)
≥99.0% (area%, UK sourced material)
Assay from Supplier's CofA
≥99.0% (wt% GC, US sourced material)
Identification (FTIR)
Conforms

概要

Trifluoroethanol serves as a solvent and a raw material in organic chemistry and biology. TFE is a solvent of choice for hydrogen peroxide-mediated oxidations of sulfides. Trifluoroethanol acts as a protein denaturant. It is used in the manufacture of certain pharmaceuticals and drug substances. The drug fluromer, which is 2,2,2-trifluoro-1-vinyloxyethane, is the vinyl ether of trifluorethanol. It is an effective solvent for peptides and proteins, and used for NMR-based protein folding studies, and in the manufacture of nylon. As a source of the trifluoromethyl group, it is employed in several organic reactions, for example in Still-Gennari modification of Horner-Wadsworth-Emmons reaction (HWE) reaction.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Trifluoroethanol serves as a solvent and a raw material in organic chemistry and biology. TFE is a solvent of choice for hydrogen peroxide-mediated oxidations of sulfides. Trifluoroethanol acts as a protein denaturant. It is used in the manufacture of certain pharmaceuticals and drug substances. The drug fluromer, which is 2,2,2-trifluoro-1-vinyloxyethane, is the vinyl ether of trifluorethanol. It is an effective solvent for peptides and proteins, and used for NMR-based protein folding studies, and in the manufacture of nylon. As a source of the trifluoromethyl group, it is employed in several organic reactions, for example in Still-Gennari modification of Horner-Wadsworth-Emmons reaction (HWE) reaction.

Solubility
Miscible with water, ethers, ketones, alcohols and chloroform.

Notes
Moisture sensitive.
RUO – Research Use Only

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