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Thermo Scientific Chemicals
Thymidine, 99%
CAS: 50-89-5 | C10H14N2O5 | 242.23 g/mol
化学物質識別子
CAS50-89-5
IUPAC Name1-[4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione
Molecular FormulaC10H14N2O5
InChI KeyIQFYYKKMVGJFEH-UHFFFAOYNA-N
SMILESCC1=CN(C2CC(O)C(CO)O2)C(=O)NC1=O
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仕様
スペックシート
スペックシートAppearance (Color)White to pale cream
FormPowder or crystals or crystalline powder
Assay (HPLC)≥98.5%
Optical Rotation+17° to +21° (c= 1 in water)
Thymidine is used in the syntheses of active pharmaceutical ingredient such as zidovudine. It also pairs with deoxyadenosine in double-stranded deoxyribonucleic acid. It is used to synchronize the cells in G1/early S phase in cell biology.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
Thymidine is used in the syntheses of active pharmaceutical ingredient such as zidovudine. It also pairs with deoxyadenosine in double-stranded deoxyribonucleic acid. It is used to synchronize the cells in G1/early S phase in cell biology.
Solubility
Soluble in water, methanol, hot ethanol, hot acetone, hot ethyl acetate, pyridine, glacial acetic acid and hydrochloric acid. Slightly soluble in hot chloroform .
Notes
Store in a cool place. Incompatible with strong oxidizing agents.
Thymidine is used in the syntheses of active pharmaceutical ingredient such as zidovudine. It also pairs with deoxyadenosine in double-stranded deoxyribonucleic acid. It is used to synchronize the cells in G1/early S phase in cell biology.
Solubility
Soluble in water, methanol, hot ethanol, hot acetone, hot ethyl acetate, pyridine, glacial acetic acid and hydrochloric acid. Slightly soluble in hot chloroform .
Notes
Store in a cool place. Incompatible with strong oxidizing agents.
RUO – Research Use Only
General References:
- Datta, D.; Bera, R. K.; Jana, S.; Manna, B.; Roy, D.; Anoop, A.; Raj, C. R.; Pathak, T. A Rationally Designed Thymidine-Based Self-Assembled Monolayer on a Gold Electrode for Electroanalytical Applications. Chem. Asian J. 2015, 10 (7), 1554-1560.
- Salpin, J. Y.; Scuderi, D. Structure of protonated thymidine characterized by infrared multiple photon dissociation and quantum calculations. Rapid Commun. Mass Spectrom. 2015, 29 (20), 1898-1904.