4-Hydroxyquinoline-2-carboxylic acid hydrate, 98%
4-Hydroxyquinoline-2-carboxylic acid hydrate, 98%
4-Hydroxyquinoline-2-carboxylic acid hydrate, 98%
4-Hydroxyquinoline-2-carboxylic acid hydrate, 98%
Thermo Scientific Chemicals

4-Hydroxyquinoline-2-carboxylic acid hydrate, 98%

CAS: 345909-35-5 | C10H7NO3 | 189.17 g/mol
製品番号(カタログ番号) A12602.14
または、製品番号A12602-14
価格(JPY)
-
見積もりを依頼する
数量:
25 g
一括またはカスタム形式をリクエストする
化学物質識別子
CAS345909-35-5
IUPAC Name4-hydroxyquinoline-2-carboxylic acid
Molecular FormulaC10H7NO3
InChI KeyHCZHHEIFKROPDY-UHFFFAOYSA-N
SMILESOC(=O)C1=NC2=CC=CC=C2C(O)=C1
さらに表示
Appearance (Color)Dark cream to cream to yellow to green to pale brown to pale gray to gray
FormPowder
Assay (Silylated GC)≥97.5%
Identification (FTIR)Conforms
Water Content (Karl Fischer Titration)4.54-12.5% (0.5-1.5 waters)
さらに表示
Broad spectrum excitatory amino acid antagonist4-Hydroxyquinoline-2-carboxylic acid hydrate is used as an intermediate in synthetic chemistry. It acts as an antiexcitotoxic and anticonvulsant. It finds application in certain neurobiological disorders therapy.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Solubility
Soluble in hot ethanol and water. Insoluble in ether. 

Notes
Incompatible with oxidizing agents.
RUO – Research Use Only

General References:

  1. Pesek, J.; Svoboda, J.; Sattler, M.; Bartram, S.; Boland, W. Biosynthesis of 8-hydroxyquinoline-2-carboxylic acid, an iron chelator from the gut of the lepidopteran Spodoptera littoralis. Org. Biomol. Chem. 2015, 13 (1), 178-184.
  2. Tajti, J.; Majlath, Z.; Szok, D.; Csati, A.; Toldi, J.; Fulop, F.; Vecsei, L. Novel Kynurenic Acid Analogues in the Treatment of Migraine and Neurodegenerative Disorders: Preclinical Studies and Pharmaceutical Design. Curr. Pharm. Des. 2015, 21 (17), 2250-2258.