Benzimidazole, 99%
Benzimidazole, 99%
Benzimidazole, 99%
Thermo Scientific Chemicals

Benzimidazole, 99%

CAS: 51-17-2 | C7H6N2 | 118.14 g/mol
製品番号(カタログ番号) A12763.0B
または、製品番号A12763-0B
価格(JPY)
-
数量:
1000 g
一括またはカスタム形式をリクエストする
化学物質識別子
CAS51-17-2
IUPAC Name1H-1,3-benzodiazole
Molecular FormulaC7H6N2
InChI KeyHYZJCKYKOHLVJF-UHFFFAOYSA-N
SMILESN1C=NC2=CC=CC=C12
さらに表示
Appearance (Color)White to cream to brown
FormCrystals or powder or crystalline powder
Assay (Non-aqueous acid-base Titration)≥98.5 to ≤101.5%
Identification (FTIR)Conforms
Melting Point (clear melt)169-174?C
さらに表示
Benzimidazole is a building block for making anthelmintic drugs like albendazole, mebendazole and triclabendazole and anti-ulcer drugs like pantoprazole, rabeprazole, lansoprazole and omeprazole. It is used in the preparation of pyrene derived benzimidazole linked polymers (BILPs), which are used for selective carbon dioxide separation applications due to their properties like porous materials, regenerability and sorbent selection parameters.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Benzimidazole is a building block for making anthelmintic drugs like albendazole, mebendazole and triclabendazole and anti-ulcer drugs like pantoprazole, rabeprazole, lansoprazole and omeprazole. It is used in the preparation of pyrene derived benzimidazole linked polymers (BILPs), which are used for selective carbon dioxide separation applications due to their properties like porous materials, regenerability and sorbent selection parameters.

Solubility
Sparingly soluble in water.

Notes
Store in cool place. Incompatible with strong oxidizing agents.
RUO – Research Use Only

General References:

  1. Chaudhry, U.; Redman, E. M.; Raman, M.; Gilleard, J. S. Genetic evidence for the spread of a benzimidazole resistance mutation across southern India from a single origin in the parasitic nematode Haemonchus contortus. Int J Parasitol 2015, 45 (11), 721-728.
  2. Dam, C. S.; Henarejos, S. A. P.; Tsolakou, T.; Segato, C. A.; Gammelgaard, B.; Yellol, G. S.; Ruiz, J.; Lambert, I. H.; Sturup, S. In vitro characterization of a novel C,N-cyclometalated benzimidazole Ru(II) arene complex: stability, intracellular distribution and binding, effects on organic osmolyte homeostasis and induction of apoptosis. Metallomics 2015, 7 (5), 885-895.