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Thermo Scientific Chemicals
5-Sulfosalicylic acid dihydrate, 98%
CAS: 5965-83-3 | C9H14O6S | 250.27 g/mol
化学物質識別子
CAS5965-83-3
IUPAC Name2-hydroxy-5-sulfobenzoic acid; bis(methane)
Molecular FormulaC9H14O6S
InChI KeyNFYHZVWMQHQKRU-UHFFFAOYSA-N
SMILESC.C.OC(=O)C1=CC(=CC=C1O)S(O)(=O)=O
さらに表示
仕様
スペックシート
スペックシートAssay (Aqueous acid-base Titration)≥97.5 to ≤102.5%
Identification (FTIR)Conforms
Melting Point (clear melt)99-112?C
Water Content (Karl Fischer Titration)14-22%
FormCrystals or powder or crystalline powder
さらに表示
5-Sulfosalicylic acid dihydrate may be employed for the quantification of doxorubicin derived from PEGylated liposomal doxorubicin (Doxil) and its major metabolite in human plasma by HPLC. It may be used in the preparation of poly[[tris(di-2-pyridylamine)tris([?]-5-sulfonatosalicylato)tricopper(II)] trihydrate]. Also used as an intermediate synthesis of bulk drugs, surfactant and additive for lubricating grease.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
5-Sulfosalicylic acid dihydrate may be employed for the quantification of doxorubicin derived from PEGylated liposomal doxorubicin (Doxil) and its major metabolite in human plasma by HPLC. It may be used in the preparation of poly[[tris(di-2-pyridylamine)tris([μ]-5-sulfonatosalicylato)tricopper(II)] trihydrate]. Also used as an intermediate synthesis of bulk drugs, surfactant and additive for lubricating grease.
Solubility
Soluble in water
Notes
Light Sensitive, store in dark. Store in cool, dry place in tightly closed container. Store away from strong bases and oxidizing agent.
5-Sulfosalicylic acid dihydrate may be employed for the quantification of doxorubicin derived from PEGylated liposomal doxorubicin (Doxil) and its major metabolite in human plasma by HPLC. It may be used in the preparation of poly[[tris(di-2-pyridylamine)tris([μ]-5-sulfonatosalicylato)tricopper(II)] trihydrate]. Also used as an intermediate synthesis of bulk drugs, surfactant and additive for lubricating grease.
Solubility
Soluble in water
Notes
Light Sensitive, store in dark. Store in cool, dry place in tightly closed container. Store away from strong bases and oxidizing agent.
RUO – Research Use Only
General References:
- David L Chin et. al. Rapid determination of PEGylated liposomal doxorubicin and its major metabolite in human plasma by ultraviolet-visible high-performance liquid chromatography. Journal of Chromatography B. 2002, 779(2), 259-269.
- Fan S-R; and Zhu L-G. Poly [[tris (di-2-pyridylamine) tris (-5-sulfonatosalicylato) tricopper (II)] trihydrate]. Acta Crystallogr. Sect. E Struct. Rep. Online, 2004, 61 (1), m174-m176.
- Deproteinization reagent: J. Chromat., 74, 255 (1973); 570, 285 (1991). Spray reagent for detection of sugars on TLC: J. Chromat., 315, 401 (1985).
- Acid catalyst, alternative to tosic acid in certain esterification and acetalization reactions: Org. Synth. Coll., 1, 246 (1941); J. Am. Chem. Soc., 76, 743 (1954); 80, 6613 (1958); J. Org. Chem., 28, 2425 (1963).