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Thermo Scientific Chemicals
10-Undecynoic acid, 96%
CAS: 2777-65-3 | C11H18O2 | 182.263 g/mol
化学物質識別子
CAS2777-65-3
IUPAC Nameundec-10-ynoate
Molecular FormulaC11H17O2
InChI KeyOAOUTNMJEFWJPO-UHFFFAOYSA-M
SMILES[O-]C(=O)CCCCCCCCC#C
さらに表示
仕様
スペックシート
スペックシートAppearance (Color)White to cream to pale yellow or pale brown
FormPowder
Assay (Silylated GC)≥95.0%
Melting Point (clear melt)40-45?C
Assay (Aqueous acid-base Titration)≥95.0% to ≤105.0%
10-Undecynoic acid may be employed as a biochemical probe in an assay for the microsomal hydroxylation of lauric acid (LA), based on HPLC with flow-through radiochemical detection. It was employed as model compound to investigate the microwave assisted surface click reactions catalyzed with Cu(II)/sodium L-ascorbate. It is reported as highly selective irreversible inhibitor of hepatic ω- and ω-1-lauric acid hydroxylases.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
10-Undecynoic acid may be employed as a biochemical probe in an assay for the microsomal hydroxylation of lauric acid (LA), based on HPLC with flow-through radiochemical detection. It was employed as model compound to investigate the microwave assisted surface click reactions catalyzed with Cu(II)/sodium L-ascorbate. It is reported as highly selective irreversible inhibitor of hepatic ω- and ω-1-lauric acid hydroxylases.
Solubility
Sparingly Soluble in water.
Notes
Store at 4°C. Store away from incompatible materials such as oxidizing agents
10-Undecynoic acid may be employed as a biochemical probe in an assay for the microsomal hydroxylation of lauric acid (LA), based on HPLC with flow-through radiochemical detection. It was employed as model compound to investigate the microwave assisted surface click reactions catalyzed with Cu(II)/sodium L-ascorbate. It is reported as highly selective irreversible inhibitor of hepatic ω- and ω-1-lauric acid hydroxylases.
Solubility
Sparingly Soluble in water.
Notes
Store at 4°C. Store away from incompatible materials such as oxidizing agents
RUO – Research Use Only
General References:
- P R Ortiz de Montellano; N O Reich. Specific inactivation of hepatic fatty acid hydroxylases by acetylenic fatty acids.Journal of Biological Chemistry.1984, 259 (7), 4136-4141.
- Lenart J; Pikuła S 10-Undecynoic acid, an inhibitor of cytochrome P450 4A1, inhibits ethanolamine-specific phospholipid base exchange reaction in rat liver microsomes.Acta Biochimica Polonica.1999, 46 (1), 203-210.
- For use in the synthesis of long-chain ω-hydroxy acids, by acetylenic coupling with bromoacetylenic alcohols (from hypobromite bromination of alkynols), see: Synthesis, 230 (1984).