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Thermo Scientific Chemicals
Formic acid hydrazide, 98%
CAS: 624-84-0 | CH4N2O | 60.056 g/mol
化学物質識別子
CAS624-84-0
IUPAC Nameformohydrazide
Molecular FormulaCH4N2O
InChI KeyXZBIXDPGRMLSTC-UHFFFAOYSA-N
SMILESNNC=O
さらに表示
仕様
スペックシート
スペックシートAppearance (Color)White to pale pink
FormCrystals or powder or crystalline powder or flakes
Assay (Hydrazine)≥97.5 to ≤102.5%
Identification (FTIR)Conforms
Melting Point (clear melt)53.0-60.0?C
Formic acid hydrazide is used as a precursor in the preparation of 1,2,4-triazole derivatives. It is also used in the synthesis of 6-N-formylamino-12,13-dihydro-1,11-dihydroxy-13-(beta-D-glucopyranosyl)-5H-indolo[2,3-a]-pyrrolo[3,4-c]carbazole-5,7(6H)-dione, which is an anticancer agent.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
Formic acid hydrazide is used as a precursor in the preparation of 1,2,4-triazole derivatives. It is also used in the synthesis of 6-N-formylamino-12,13-dihydro-1,11-dihydroxy-13-(beta-D-glucopyranosyl)-5H-indolo[2,3-a]-pyrrolo[3,4-c]carbazole-5,7(6H)-dione, which is an anticancer agent.
Solubility
Soluble in water, ethanol and acetone.
Notes
Hygroscopic. Incompatible with strong oxidizing agents and strong bases.
Formic acid hydrazide is used as a precursor in the preparation of 1,2,4-triazole derivatives. It is also used in the synthesis of 6-N-formylamino-12,13-dihydro-1,11-dihydroxy-13-(beta-D-glucopyranosyl)-5H-indolo[2,3-a]-pyrrolo[3,4-c]carbazole-5,7(6H)-dione, which is an anticancer agent.
Solubility
Soluble in water, ethanol and acetone.
Notes
Hygroscopic. Incompatible with strong oxidizing agents and strong bases.
RUO – Research Use Only
General References:
- Bokor, É.; Fekete, A.; Varga, G.; Szőcs, B.; Czifrák, K.; Komáromi, I.; Somsák, L. C-(beta-D-Glucopyranosyl)formamidrazones, formic acid hydrazides and their transformations into 3-(beta-D-glucopyranosyl)-5-substituted-1,2,4-triazoles: a synthetic and computational study. Tetrahedron 2013, 69 (48), 10391-10404.
- Guin, S.; Rout, S. K.; Gogoi, A.; Nandi, S.; Ghara, K. K.; Patel, B. K. Desulfurization Strategy in the Construction of Azoles Possessing Additional Nitrogen, Oxygen or Sulfur using a Copper(I) Catalyst. Adv. Synth. Catal. 2012, 354 (14-15), 2757-2770.