2,4-Dichloropyrimidine, 98+%
2,4-Dichloropyrimidine, 98+%
2,4-Dichloropyrimidine, 98+%
Thermo Scientific Chemicals

2,4-Dichloropyrimidine, 98+%

CAS: 3934-20-1 | C4H2Cl2N2 | 148.974 g/mol
数量:
5 g
10 g
50 g
250 g
製品番号(カタログ番号) A15131.06
または、製品番号A15131-06
価格(JPY)
-
数量:
5 g
一括またはカスタム形式をリクエストする
化学物質識別子
CAS3934-20-1
IUPAC Name2,4-dichloropyrimidine
Molecular FormulaC4H2Cl2N2
InChI KeyBTTNYQZNBZNDOR-UHFFFAOYSA-N
SMILESClC1=CC=NC(Cl)=N1
さらに表示
Appearance (Color)White to yellow
FormCrystals or crystalline powder and/or chunks
Assay (GC)≥98.0%
Identification (FTIR)Conforms
Melting Point (clear melt)57-62?C
さらに表示
2,4-Dichloropyrimidine is used in the synthesis of medicinally important 4-aryl-5-pyrimidinylimidazoles. It undergoes effective one-pot, regioselective double Suzuki coupling reaction to yield diarylated pyrimidines.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
2,4-Dichloropyrimidine is used in the synthesis of medicinally important 4-aryl-5-pyrimidinylimidazoles. It undergoes effective one-pot, regioselective double Suzuki coupling reaction to yield diarylated pyrimidines.

Solubility
Soluble in water (partly), methanol, chloroform, and ethyl acetate.

Notes
Moisture Sensitive. Keep container tightly closed. Store in cool, dry conditions in well sealed containers.
RUO – Research Use Only

General References:

  1. Xiaohu Deng.; Neelakandha S. Mani. An Efficient Route to 4-Aryl-5-pyrimidinylimidazoles via Sequential Functionalization of 2,4-Dichloropyrimidine. Org. Lett. 2006, 8, (2), 269-272.
  2. Zhi-Hui Peng.; Michel Journet.; Guy Humphrey. A Highly Regioselective Amination of 6-Aryl-2,4-dichloropyrimidine. Org. Lett. 2006, 8, (3), 395-398.