Search
元素の検索
構造の検索
Thermo Scientific Chemicals
1-Chloro-4-nitrobenzene, 98+%
CAS: 100-00-5 | C6H4ClNO2 | 157.553 g/mol
化学物質識別子
CAS100-00-5
IUPAC Name1-chloro-4-nitrobenzene
Molecular FormulaC6H4ClNO2
InChI KeyCZGCEKJOLUNIFY-UHFFFAOYSA-N
SMILES[O-][N+](=O)C1=CC=C(Cl)C=C1
さらに表示
仕様
スペックシート
スペックシートMelting Point80.0-86.0?C
FormCrystals or crystalline powder and/or coarse granular solid or flakes
Identification (FTIR)Conforms
Appearance (Color)White to yellow
Assay (GC)≥98.0%
1-Chloro-4-nitrobenzene is an important intermediate used in the preparation of 2,4-dinitrochlorobenzene and 3,4-dichloronitrobenzene. It is used as a raw material in the preparation of 4-nitrodiphenylamine, 4-chloroaninline and (4-[(4-aminobenzene)sulfonyl]aniline). It serves as a common antioxidant, which is found in rubber.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
1-Chloro-4-nitrobenzene is an important intermediate used in the preparation of 2,4-dinitrochlorobenzene and 3,4-dichloronitrobenzene. It is used as a raw material in the preparation of 4-nitrodiphenylamine, 4-chloroaninline and (4-[(4-aminobenzene)sulfonyl]aniline). It serves as a common antioxidant, which is found in rubber.
Solubility
Soluble in boiling hot ethanol, ether, toluene, acetone, organic solvents and carbon disulfide. Sparingly soluble in cold alcohol. Insoluble in water.
Notes
Incompatible with strong oxidizing agents and strong bases.
1-Chloro-4-nitrobenzene is an important intermediate used in the preparation of 2,4-dinitrochlorobenzene and 3,4-dichloronitrobenzene. It is used as a raw material in the preparation of 4-nitrodiphenylamine, 4-chloroaninline and (4-[(4-aminobenzene)sulfonyl]aniline). It serves as a common antioxidant, which is found in rubber.
Solubility
Soluble in boiling hot ethanol, ether, toluene, acetone, organic solvents and carbon disulfide. Sparingly soluble in cold alcohol. Insoluble in water.
Notes
Incompatible with strong oxidizing agents and strong bases.
RUO – Research Use Only
General References:
- The Cl substituent is activated to nucleophilic substitution by the p-nitro-group, and can be displaced under relatively mild conditions. For displacement by phenoxide, see: Org. Synth. Coll., 2, 445 (1943). For displacement by alkoxide in good yield, in the presence of TBAB or 18-crown-6, see: J. Org. Chem., 48, 3022 (1983).
- Büldt, L. A.; Prescimone, A.; Neuburger, M.; Wenger, O. S. Photoredox Properties of Homoleptic d6 Metal Complexes with the Electron-Rich 4,4',5,5'-Tetramethoxy-2,2'-bipyridine Ligand. Eur. J. Inorg. Chem. 2015, 2015 (28), 4666-4677.
- Zhuo, L.; Kou, K.; Yao, P.; Wu, G.; Wang, Y. Preparation and thermal decomposition kinetics research of pyridine-containing polyimide. J. Therm. Anal. Calorim. 2015, 119 (3), 2039-2051.