3-Amino-2-chloropyridine, 98+%

Name: 3-Amino-2-chloropyridine, 98+%
SKU: A15830.30

CAS: 6298-19-7 | C5H5ClN2 | 128.56 g/mol

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数量:

10 g

50 g

250 g

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製品番号（カタログ番号） A15830.30

または、製品番号A15830-30

価格（JPY）

数量:

250 g

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化学物質識別子

CAS6298-19-7

IUPAC Name2-chloropyridin-3-amine

Molecular FormulaC5H5ClN2

InChI KeyMEQBJJUWDCYIAB-UHFFFAOYSA-N

SMILESNC1=CC=CN=C1Cl

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仕様

スペックシート

Assay (GC)≥98.0%

Appearance (Color)White to cream to brown or pink

FormCrystals or crystalline powder and/or chunks

CommentMay contain slight discolored particles as part of manufacturing process

Melting Point76-82°C

It is an intermediate of medicine and agricultural chemicals. It is involved in the Suzuki-Miyaura cross-coupling reactions of heteroaryl compounds.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
It is an intermediate of medicine and agricultural chemicals. It is involved in the Suzuki-Miyaura cross-coupling reactions of heteroaryl compounds.

Solubility
Soluble in methanol and water. (30 g/L).

Notes
Store at room temperature. Keep away from oxidizing agents.

RUO – Research Use Only

General References:

J. M. Bakke.; J. Riha. Preparation of 4-substituted 3-amino-2-chloropyridines, synthesis of a nevirapine analogue.Journal of Heterocyclic Chemistry. 2001, 38 (1),99-104 .
Takahiro Itoh.; Toshiaki Mase. Direct synthesis of hetero-biaryl compounds containing an unprotected NH2 group via Suzuki-Miyaura reaction. Tetrahedron Lett. 2005, 46 (20),3573-3577 .
Reaction with aroyl halides, followed by cyclization with PPSE (see Hexamethyl disiloxane, A11848), gives oxazolo[5,4-b]pyridines in high yield: Synthesis, 64 (1990):