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Thermo Scientific Chemicals
N-(Trimethylsilyl)dimethylamine, 95%
CAS: 2083-91-2 | C5H15NSi | 117.27 g/mol
化学物質識別子
CAS2083-91-2
IUPAC Namedimethyl(trimethylsilyl)amine
Molecular FormulaC5H15NSi
InChI KeyKAHVZNKZQFSBFW-UHFFFAOYSA-N
SMILESCN(C)[Si](C)(C)C
さらに表示
仕様
スペックシート
スペックシートAssay (GC)≥94.0% (non-U.S. specification)
Infrared spectrumConforms (U.S. specification)
Refractive Index1.3950-1.4010 @ 20°C (non-U.S. specification)
Assay from Supplier's CofA≥94.0% (U.S. specification)
FormLiquid
さらに表示
N,N-Dimethyltrimethylsilylamine was used in the synthesis of phosphoramidite. It was also employed as a reagent in the preparation of iminium salts and amides as well as for the silylation of polymers. A combination of N-(trimethylsilyl)dimethylamine and MeI was also effective to give p-methylbenzoic acid with a 85% yield based on 90% conversion from the corresponding Me ester. DETA has been treated with N-(trimethylsilyl)-dimethylamine to yield mono-, di- and tri- silylated derivatives
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
N,N-Dimethyltrimethylsilylamine was used in the synthesis of phosphoramidite. It was also employed as a reagent in the preparation of iminium salts and amides as well as for the silylation of polymers. A combination of N-(trimethylsilyl)dimethylamine and MeI was also effective to give p-methylbenzoic acid with a 85% yield based on 90% conversion from the corresponding Me ester. DETA has been treated with N-(trimethylsilyl)-dimethylamine to yield mono-, di- and tri- silylated derivatives
Solubility
Hydrolyzes in water.
Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents, water, moisture.
N,N-Dimethyltrimethylsilylamine was used in the synthesis of phosphoramidite. It was also employed as a reagent in the preparation of iminium salts and amides as well as for the silylation of polymers. A combination of N-(trimethylsilyl)dimethylamine and MeI was also effective to give p-methylbenzoic acid with a 85% yield based on 90% conversion from the corresponding Me ester. DETA has been treated with N-(trimethylsilyl)-dimethylamine to yield mono-, di- and tri- silylated derivatives
Solubility
Hydrolyzes in water.
Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents, water, moisture.
RUO – Research Use Only
General References:
- Fourrey JL ,; Varenne J. A new and general procedure for the preparation of deoxynucleoside phosphoramidites.. Tetrahedron Lett. 1983, 24 (19), 1963-1966.
- Arihiro Iwata,; Joji Ohshita,; Heqing Tang,; Atsutaka Kunai. Ring-Opening Iodo- and Bromosilation of Lactones for the Formation of Silyl Haloalkanoates. J. Org. Chem. 2002, 67 (11), 3927-3929.
- Reagent for siliylation of a wide range of functional groups, without the need for added base, useful for amino acids: J. Chromat. Sci., 7, 704 (1969). In the presence of the hindered ligand 2-(Di-tert-butyl phosphino) biphenyl , L19758, Pd-catalyzed cross-coupling reactions with aryl halides to give substituted N,N-dimethylanilines have been effected: Chem. Commun., 1976 (2004).