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Thermo Scientific Chemicals
2-Adamantanamine hydrochloride, 98+%
CAS: 10523-68-9 | C10H18ClN | 187.71 g/mol
化学物質識別子
CAS10523-68-9
IUPAC Namehydrogen adamantan-2-amine chloride
Molecular FormulaC10H18ClN
InChI KeyWLDWDRZITJEWRJ-UHFFFAOYSA-N
SMILES[H+].[Cl-].NC1C2CC3CC(C2)CC1C3
さらに表示
仕様
スペックシート
スペックシートAssay (Titration ex Chloride)≥98.0 to ≤102.0%
Appearance (Color)White
FormCrystals or powder or crystalline powder
2-Adamantylamine hydrochloride was used to prepare 2-adamantylamide of 2?-(carboxymethoxime)-olivomycin I. The HPLC assay of 2-adamantylamine hydrochloride after pre-column derivatization with 4-fluoro-7-nitro-2,1,3-benzoxadiazole has been studied. It is also used as an important raw material and intermediate used in organic Synthesis, pharmaceuticals, agrochemicals and dyestuff.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
2-Adamantylamine hydrochloride was used to prepare 2-adamantylamide of 2′-(carboxymethoxime)-olivomycin I. The HPLC assay of 2-adamantylamine hydrochloride after pre-column derivatization with 4-fluoro-7-nitro-2,1,3-benzoxadiazole has been studied. It is also used as an important raw material and intermediate used in organic Synthesis, pharmaceuticals, agrochemicals and dyestuff.
Solubility
Soluble in water.
Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Stable under recommended storage conditions. Keep away from oxidizing agents.
2-Adamantylamine hydrochloride was used to prepare 2-adamantylamide of 2′-(carboxymethoxime)-olivomycin I. The HPLC assay of 2-adamantylamine hydrochloride after pre-column derivatization with 4-fluoro-7-nitro-2,1,3-benzoxadiazole has been studied. It is also used as an important raw material and intermediate used in organic Synthesis, pharmaceuticals, agrochemicals and dyestuff.
Solubility
Soluble in water.
Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Stable under recommended storage conditions. Keep away from oxidizing agents.
RUO – Research Use Only
General References:
- JS Scott.; J deSchoolmeester.; E Kilgour. Novel Acidic 11β-Hydroxysteroid Dehydrogenase Type 1 (11β-HSD1) Inhibitor with Reduced Acyl Glucuronide Liability: The Discovery of 4-[4-(2-Adamantylcarbamoyl)-5-tert-butyl-pyrazol-1-yl]benzoic Acid (AZD8329). J. Med. Chem.201255 (22), 10136-10147.
- SW Kwon.; SK Kang.; JH Lee.; JH Bok.; CH Kim. Synthesis and 11β hydroxysteroid dehydrogenase 1 inhibition of thiazolidine derivatives with an adamantyl group. Bioorganic & Medicinal Chemistry Letters. 201121 (1), 435-439.