2-Amino-2-methyl-1-propanol is used for the preparation of buffer solution and in cosmetics. It is also used in ATR-FTIR spectroscopic investigation of the carbon monoxide absorption characteristics of a series of heterocyclic diamines.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
2-Amino-2-methyl-1-propanol is used for the preparation of buffer solution and in cosmetics. It is also used in ATR-FTIR spectroscopic investigation of the carbon monoxide absorption characteristics of a series of heterocyclic diamines.
Solubility
Immiscible with water. Miscible with alcohols.
Notes
Incompatible withoxidizing agents, strong acids, copper, brass and aluminum.
RUO – Research Use Only
General References:
- Buffer and phosphate acceptor in assay of phosphatases: Methods of Enzymatic Analysis, 3rd ed., H. U. Bergmeyer, Ed., Verlag Chemie, Weinheim (1984), vol. 4, p76.
- Precursor of 2-substituted-4,4-dimethyl-2-oxazoline derivatives of carboxylic acids: J. Org. Chem., 39, 2787 (1974), developed by Meyers. The oxazoline, which is readily formed with the acid chloride and thionyl chloride, is stable to base, organometallic reagents, etc., but readily cleaved by dilute acid. For further information on the reactivity of these derivatives, see 2,4,4-Trimethyl-2-oxazoline, L00181.
- 2-Aryl-4,4-dimethyl-2-oxazolines are activated towards ortho-lithiation: J. Org. Chem., 40, 3058 (1975). Methoxy- or fluoro-substituents in the ortho-position are readily substitutied by organolithiums or Grignards, providing a versatile route to biaryls: J. Am. Chem. Soc ., 97, 7383 (1975). For examples, see: Org. Synth. Coll., 9, 258 (1998). The oxazoline can also be converted to an aldehyde by methylation and borohydride reduction.
- For reviews of the use of oxazolines in synthesis, see: Angew. Chem. Int. Ed., 15, 270 (1976); Tetrahedron, 41, 837 (1985); 50, 2297 (1994)./
- Conway, W.; Bruggink, S.; Beyad, Y.; Luo, W.; Cabrera, I. M., Puxty, G.; Feron, P. CO2 absorption into aqueous amine blended solutions containing monoethanolamine (MEA), N, N-dimethylethanolamine (DMEA), N, N-diethylethanolamine (DEEA) and 2-amino-2-methyl-1-propanol (AMP) for post-combustion capture processes. Chem. Eng. Sci. 2015, 126, 446-454.
- Halim, H. N. A.; Shariff, A. M.; Bustam, M. A. High pressure CO2 absorption from natural gas using piperazine promoted 2-amino-2-methyl-1-propanol in a packed absorption column. Sep. Purif. Technol. 2015, 152, 87-93.