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Thermo Scientific Chemicals
D-(-)-Ribose, 98%
CAS: 50-69-1 | C5H10O5 | 150.13 g/mol
化学物質識別子
CAS50-69-1
IUPAC Name(3R,4S,5R)-5-(hydroxymethyl)oxolane-2,3,4-triol
Molecular FormulaC5H10O5
InChI KeyHMFHBZSHGGEWLO-ZHZWXSSZNA-N
SMILESOC[C@H]1OC(O)[C@H](O)[C@@H]1O
さらに表示
仕様
スペックシート
スペックシートAppearance (Color)White to cream to yellow to pale brown
FormPowder or crystalline powder
Assay (Silylated GC)≥97.5%
Identification (FTIR)Conforms
Optical Rotation-18° to -22° (c=10 in water, NH4OH)
D-(-)-Ribose is mainly used as a very basic source of metabolism of life. It is also used as a precursor for virazole, adenosine, thymidine, cytidine, fluoro-thymidine, 2-methyl adenosine, pyrromonazole toxina and adenosine methionine. It is further used in the synthesis of vitamin B2 (riboflavin), tetra-O-acetyl-ribose and nucleoside. It finds application as food additives and as supplement in cell culture.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
D-(-)-Ribose is mainly used as a very basic source of metabolism of life. It is also used as a precursor for virazole, adenosine, thymidine, cytidine, fluoro-thymidine, 2-methyl adenosine, pyrromonazole toxina and adenosine methionine. It is further used in the synthesis of vitamin B2 (riboflavin), tetra-O-acetyl-ribose and nucleoside. It finds application as food additives and as supplement in cell culture.
Solubility
Soluble in water. Insoluble in ether.
Notes
Hygroscopic. Incompatible with strong oxidizing agents. Store in a cool place.
D-(-)-Ribose is mainly used as a very basic source of metabolism of life. It is also used as a precursor for virazole, adenosine, thymidine, cytidine, fluoro-thymidine, 2-methyl adenosine, pyrromonazole toxina and adenosine methionine. It is further used in the synthesis of vitamin B2 (riboflavin), tetra-O-acetyl-ribose and nucleoside. It finds application as food additives and as supplement in cell culture.
Solubility
Soluble in water. Insoluble in ether.
Notes
Hygroscopic. Incompatible with strong oxidizing agents. Store in a cool place.
RUO – Research Use Only
General References:
- For an evaluation of the potential of D-ribose as an enantiopure building block for construction of the C-ring of taxol, see: J. Org. Chem., 60, 7849 (1995).
- Downey, A. M.; Richter, C.; Pohl, R.; Mahrwald, R.; Hocek, M. Direct One-Pot Synthesis of Nucleosides from Unprotected or 5-O-Monoprotected D-Ribose. Org. Lett. 2015, 17 (18), 4604-4607.
- Sinatra, S. T.; Caiazzo, C. D-Ribose Supplementation in the Equine: Lack of Effect on Glycated Plasma Proteins Suggesting Safety in Humans. J. Am. Coll. Nutr. 2015, 34 (2), 108-112.