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Oncomine™ Comprehensive Assay Plus, automated library preparation
The Oncomine Comprehensive Assay Plus is a targeted, next-generation sequencing (NGS) assay that provides a comprehensive genomic profiling solution appropriate詳細を見る
| 製品番号（カタログ番号） | 数量 |
|---|---|
| A49667 | 32 samples |
製品番号（カタログ番号） A49667
価格（JPY）
-
数量:
32 samples
The Oncomine Comprehensive Assay Plus is a targeted, next-generation sequencing (NGS) assay that provides a comprehensive genomic profiling solution appropriate for formalin-fixed paraffin-embedded (FFPE) tissues from solid tumors. The assay detects multiple biomarkers associated with targeted and immune checkpoint therapies for cancer research. It allows concurrent analysis of DNA and RNA to simultaneously detect multiple types of variants in a single workflow, including single nucleotide variants (SNVs), insertions and deletions (InDels), copy number variants (CNVs), BRCA1 and BRCA2 large genomic rearrangements (LGRs), genomic instability metric (GIM), microsatellite instability (MSI), and tumor mutational burden (TMB), loss-of-heterozygosity (LOH), and gene fusions featuring FusionSync.
Key features of the assay include:
The Oncomine Comprehensive Assay Plus provides the reagents for the Ion Chef System for automated library construction from four pools—two DNA and two RNA—of multiplex PCR primers for automated preparation of amplicon libraries from formalin-fixed paraffin embedded (FFPE) tumor samples using the Ion Chef instrument. Designed to help you go from hundreds down to a few relevant cancer drivers, this assay is part of a comprehensive workflow that enables NGS data analysis from as little as 10 ng of nucleic acid per pool. The assay is optimized for sequencing on the Ion GeneStudio S5 systems with the Ion 550 Chip to enable up to four samples and a no-template control (NTC) per run.
When combined with Oncomine Reporter Software, you can focus on key drivers of cancer in your research.
From sample to answer
The Oncomine Comprehensive Assay Plus is part of an NGS workflow that helps researchers filter variant results from hundreds to just a few key cancer driver variants. Enabled by Oncomine Informatics, this filtering helps you contextualize and interpret findings to move toward the answers you need.
Learn more about Oncomine Oncology ›
Key features of the assay include:
• Profile 500+ unique genes for single gene and multi-gene biomarker insights
• Enables analysis of various single-gene variants, such as SNVs, indels, fusions, splice variants, and CNV, including both copy number gains and losses
• Detection of complex biomarkers associated with immunotherapies such as TMB and MSI
• Supports homologous recombination deficiency (HRD) research by detecting mutations in 46 HRR genes, including BRCA LGRs, and assessment genomic scarring with the genomic instability metric (GIM)
• Robust performance from as little as 20 ng of DNA/RNA isolated from FFPE samples including fine needle biopsies
• Content driven by the Oncomine Knowledgebase and experienced scientists helps assure coverage of key targets aligned to published evidence
• Highly automated workflow and streamlined bioinformatics analysis pipeline optimized for Oncomine Comprehensive Assay Plus helps deliver insights
The Oncomine Comprehensive Assay Plus provides the reagents for the Ion Chef System for automated library construction from four pools—two DNA and two RNA—of multiplex PCR primers for automated preparation of amplicon libraries from formalin-fixed paraffin embedded (FFPE) tumor samples using the Ion Chef instrument. Designed to help you go from hundreds down to a few relevant cancer drivers, this assay is part of a comprehensive workflow that enables NGS data analysis from as little as 10 ng of nucleic acid per pool. The assay is optimized for sequencing on the Ion GeneStudio S5 systems with the Ion 550 Chip to enable up to four samples and a no-template control (NTC) per run.
When combined with Oncomine Reporter Software, you can focus on key drivers of cancer in your research.
From sample to answer
The Oncomine Comprehensive Assay Plus is part of an NGS workflow that helps researchers filter variant results from hundreds to just a few key cancer driver variants. Enabled by Oncomine Informatics, this filtering helps you contextualize and interpret findings to move toward the answers you need.
Learn more about Oncomine Oncology ›
研究用途にのみご使用ください。診断目的には使用できません。
仕様
使用対象 (装置)Ion GeneStudio™ S5 Prime Systems, Ion Chef™ Instrument
ライブラリTargeted Sequencing Library (Amplicon based)
製品ラインOncomine
数量32 samples
サンプルタイプDNA, RNA
ワークフローステップライブラリ生成
Sequencing TypeNext Generation Sequencing
Unit SizeEach