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Citations & References (26)
Invitrogen™
Alpha-Bungarotoxin Conjugates
Thermo Fisher Scientific offers a broad selection of Invitrogen alpha-bungarotoxin conjugates, including Alexa Fluor and Alexa Fluor Plus conjugates.
製品番号（カタログ番号） B13423
価格（JPY）お問い合わせください ›
128,200
Each
標識または色素:
Alexa Fluor™ 594
Thermo Fisher Scientific offers a broad selection of Invitrogen alpha-bungarotoxin conjugates, including Alexa Fluor and Alexa Fluor Plus conjugates. Alpha-bungarotoxin, a 74-amino acid peptide extracted from Bungarus multicinctus venom, binds with high affinity to the alpha subunit of the nicotinic acetylcholine receptor (AChR) of neuromuscular junctions.
Our bright and photostable Alexa Fluor 555 alpha-bungarotoxin is a superior choice of probe for visualizing this receptor. Fluorescent alpha-bungarotoxin conjugates can be used to facilitate identification of nicotinic AChRs and localization of neuromuscular junctions. Conjugated alpha-bungarotoxin has been used in variety of applications, including immunofluorescence (IF), immunohistochemistry (IHC), and flow cytometry (FC).
For Research Use Only. Not for use in diagnostic procedures.
仕様
標識または色素Alexa Fluor™ 594
製品タイプコンジュゲート
タンパク質サブタイプその他のタンパク質
数量500 μg
出荷条件室温
Excitation/Emission590/617 nm
製品ラインAlexa Fluor
Unit SizeEach
組成および保存条件
フリーザー（-5～-30度）に保存し、遮光してください。
引用および参考文献 (26)
引用および参考文献
Abstract
Specification of motoneurons from human embryonic stem cells.
Journal:Nat Biotechnol
PubMed ID:15685164
'An understanding of how mammalian stem cells produce specific neuronal subtypes remains elusive. Here we show that human embryonic stem cells generated early neuroectodermal cells, which organized into rosettes and expressed Pax6 but not Sox1, and then late neuroectodermal cells, which formed neural tube-like structures and expressed both Pax6 and
Local induction of acetylcholine receptor clustering in myotube cultures using microfluidic application of agrin.
Journal:Biophys J
PubMed ID:16387765
'During neuromuscular synaptogenesis, the exchange of spatially localized signals between nerve and muscle initiates the coordinated focal accumulation of the acetylcholine (ACh) release machinery and the ACh receptors (AChRs). One of the key first steps is the release of the proteoglycan agrin focalized at the axon tip, which induces the
Absence of acetylcholinesterase at the neuromuscular junctions of perlecan-null mice.
Journal:Nat Neurosci
PubMed ID:11802174
'The collagen-tailed form of acetylcholinesterase (AChE) is concentrated at the vertebrate neuromuscular junction (NMJ), where it is responsible for rapidly terminating neurotransmission. This unique oligomeric form of AChE, consisting of three tetramers covalently attached to a collagen-like tail, is more highly expressed in innervated regions of skeletal muscle fibers, where
Ex vivo imaging of motor axon dynamics in murine triangularis sterni explants.
Journal:Nat Protoc
PubMed ID:18833201
'We provide a protocol that describes an explant system that allows the dynamics of motor axons to be imaged. This method is based on nerve-muscle explants prepared from the triangularis sterni muscle of mice, a thin muscle that covers the inside of the thorax. These explants, which can be maintained
alpha-Actinin interacts with rapsyn in agrin-stimulated AChR clustering.
Journal:Mol Brain
PubMed ID:19055765
: AChR is concentrated at the postjunctional membrane at the neuromuscular junction. However, the underlying mechanism is unclear. We show that alpha-actinin, a protein known to cross-link F-actin, interacts with rapsyn, a scaffold protein essential for neuromuscular junction formation. alpha-Actinin, rapsyn, and surface AChR form a ternary complex. Moreover, the