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Citations & References (86)
Invitrogen™
Alpha-Bungarotoxin Conjugates
Thermo Fisher Scientific offers a broad selection of Invitrogen alpha-bungarotoxin conjugates, including Alexa Fluor and Alexa Fluor Plus conjugates.
製品番号（カタログ番号） B1601
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31,800
Each
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非標識
Thermo Fisher Scientific offers a broad selection of Invitrogen alpha-bungarotoxin conjugates, including Alexa Fluor and Alexa Fluor Plus conjugates. Alpha-bungarotoxin, a 74-amino acid peptide extracted from Bungarus multicinctus venom, binds with high affinity to the alpha subunit of the nicotinic acetylcholine receptor (AChR) of neuromuscular junctions.
Our bright and photostable Alexa Fluor 555 alpha-bungarotoxin is a superior choice of probe for visualizing this receptor. Fluorescent alpha-bungarotoxin conjugates can be used to facilitate identification of nicotinic AChRs and localization of neuromuscular junctions. Conjugated alpha-bungarotoxin has been used in variety of applications, including immunofluorescence (IF), immunohistochemistry (IHC), and flow cytometry (FC).
For Research Use Only. Not for use in diagnostic procedures.
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標識または色素非標識
製品タイプコンジュゲート
タンパク質サブタイプその他のタンパク質
数量1 mg
出荷条件室温
製品ラインShuttle PIP
Unit SizeEach
組成および保存条件
冷凍庫（-5～-30℃）に保存。
引用および参考文献 (86)
引用および参考文献
Abstract
Precise localization of alpha7 nicotinic acetylcholine receptors on glutamatergic axon terminals in the rat ventral tegmental area.
Journal:J Neurosci
PubMed ID:15601930
'Alpha7 neuronal nicotinic acetylcholine receptors (nAChRs) constitute one of the predominant nAChR subtypes in the mammalian brain. Within the ventral tegmental area (VTA), nicotine application, paired with postsynaptic stimulation, contributes to a form of long-term potentiation, an effect attributed to presynaptic alpha7 nAChRs on glutamatergic afferents (Mansvelder and McGehee, 2000).
Imaging of receptor trafficking by using alpha-bungarotoxin-binding-site-tagged receptors.
Journal:Proc Natl Acad Sci U S A
PubMed ID:15563595
'alpha-Amino-3-hydroxy-5-methyl-4-isoxazole-propionate (AMPA) receptors mediate excitatory synaptic transmission and are dynamically regulated during synaptic plasticity in the CNS. The membrane trafficking of AMPA receptors to synapses is critical for the regulation of the efficacy of excitatory synaptic transmission. Direct imaging of AMPA receptors in various cell compartments is important to dissecting
alpha-Bungarotoxin binding sites in rat hippocampal and cortical cultures: initial characterisation, colocalisation with alpha 7 subunits and up-regulation by chronic nicotine treatment.
Journal:Brain Res
PubMed ID:7749744
'High density neuronal cultures from rat E18 hippocampus and cortex have been characterised with respect to cholinergic binding sites. No specific binding of [3H]nicotine or [3H]cytisine to live cells in situ was detected although the limit for detection was estimated to be 30 fmol/mg protein. Muscarinic binding sites labelled with
The short-neurotoxin-binding regions on the alpha-chain of human and Torpedo californica acetylcholine receptors.
Journal:Biochem J
PubMed ID:2012611
'The continuous regions for short-neurotoxin binding on the alpha-chains of Torpedo californica (electric ray) and human acetylcholine receptors (AChR) were localized by reaction of 125I-labelled cobrotoxin (Cot) and erabutoxin b (Eb) with synthetic overlapping peptides spanning the entire extracellular part of the respective alpha-chains. On Torpedo AChR, five Cot-binding regions
Actions of vesamicol on an alpha-bungarotoxin-sensitive neuronal nicotinic acetylcholine receptor.
Journal:J Exp Biol
PubMed ID:8228781
'Electrophysiology and binding studies were used to determine the actions of vesamicol [2-(4-phenylpiperidino)cyclohexanol (AH5183)] on an alpha-bungarotoxin-sensitive, neuronal nicotinic acetylcholine receptor in the nervous system of the cockroach, Periplaneta americana. Electrophysiological studies on an identified motor neurone revealed a reversible blocking action of (+/-)-vesamicol on the response to ionophoretically applied