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Thermo Scientific Chemicals
Sodium dichloroacetate, 96%
CAS: 2156-56-1 | C2HCl2NaO2 | 150.92 g/mol
化学物質識別子
CAS2156-56-1
IUPAC Namesodium 2,2-dichloroacetate
Molecular FormulaC2HCl2NaO2
InChI KeyLUPNKHXLFSSUGS-UHFFFAOYSA-M
SMILES[Na+].[O-]C(=O)C(Cl)Cl
さらに表示
仕様
スペックシート
スペックシートAppearance (Color)White
FormCrystals or powder or crystalline powder
Assay (Non-aqueous acid-base Titration)≥95.0 to ≤105.0%
Identification (FTIR)Conforms
Water Content (Karl Fischer Titration)≤2.0%
Sodium dichloroacetate finds medicinal application in removing warts and other skin growths. It is used as an antidote for lactic acidosis and in the treatment of stroke. It is studied as potential drugs, since it inhibits the enzyme pyruvate dehydrogenase kinase.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
Sodium dichloroacetate finds medicinal application in removing warts and other skin growths. It is used as an antidote for lactic acidosis and in the treatment of stroke. It is studied as potential drugs, since it inhibits the enzyme pyruvate dehydrogenase kinase.
Solubility
Soluble in water.
Notes
Moisture sensitive. Incompatible with strong oxidizing agents.
Sodium dichloroacetate finds medicinal application in removing warts and other skin growths. It is used as an antidote for lactic acidosis and in the treatment of stroke. It is studied as potential drugs, since it inhibits the enzyme pyruvate dehydrogenase kinase.
Solubility
Soluble in water.
Notes
Moisture sensitive. Incompatible with strong oxidizing agents.
RUO – Research Use Only
General References:
- Agnoletto, C.; Brunelli, L.; Melloni, E.; Pastorelli, R.; Casciano, F.; Rimondi, E.; Rigolin, G. M.; Cuneo, A.; Secchiero, P.; Zauli, G. The anti-leukemic activity of sodium dichloroacetate in p53mutatedull cells is mediated by a p53-independent ILF3/p21 pathway. Oncotarget 2015, 6 (4), 2385-2396.
- Ji, B.; Tang, P.; Yan, K.; Sun, G. Catalytic actions of alkaline salts in reactions between 1, 2, 3, 4-butanetetracarboxylic acid and cellulose: II. Esterification. Carbohydr. Polym. 2015, 132, 228-236.