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Thermo Scientific Chemicals
Phenylacetyl chloride, 98%
CAS: 103-80-0 | C8H7ClO | 154.59 g/mol
化学物質識別子
CAS103-80-0
IUPAC Name2-phenylacetyl chloride
Molecular FormulaC8H7ClO
InChI KeyVMZCDNSFRSVYKQ-UHFFFAOYSA-N
SMILESClC(=O)CC1=CC=CC=C1
さらに表示
仕様
スペックシート
スペックシートFormLiquid
Assay (Methyl Ester GC)≥97.5% (UK sourced material only)
Appearance (Color)Clear colorless to yellow or pink-red
Assay from Supplier's CofA≥97.5% (GC) (US sourced material only)
Assay (Titration ex Chloride)≥97.5 to ≤102,5% (UK sourced material)
さらに表示
Phenylacetyl chloride is used in the preparation of 1,2-diphenyl-ethanone by reaction with iodobenzene using tetrabutylammonium tetrafluoroborate as a phase transfer catalyst. It is widely used in the chemical industry for manufacturing dyes and pharmaceutical products. It plays an important role in the preparation of penicillin. Further, it is used to prepare esters for flavorings.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
Phenylacetyl chloride is used in the preparation of 1,2-diphenyl-ethanone by reaction with iodobenzene using tetrabutylammonium tetrafluoroborate as a phase transfer catalyst. It is widely used in the chemical industry for manufacturing dyes and pharmaceutical products. It plays an important role in the preparation of penicillin. Further, it is used to prepare esters for flavorings.
Solubility
Miscible with alcohol and ether.
Notes
Moisture sensitive. Store in a cool place.Incompatible with amines, most common metals, strong bases and strong oxidizing agents.
Phenylacetyl chloride is used in the preparation of 1,2-diphenyl-ethanone by reaction with iodobenzene using tetrabutylammonium tetrafluoroborate as a phase transfer catalyst. It is widely used in the chemical industry for manufacturing dyes and pharmaceutical products. It plays an important role in the preparation of penicillin. Further, it is used to prepare esters for flavorings.
Solubility
Miscible with alcohol and ether.
Notes
Moisture sensitive. Store in a cool place.Incompatible with amines, most common metals, strong bases and strong oxidizing agents.
RUO – Research Use Only
General References:
- Tao, Y.; Han, L.; Li, X.; Han, Y.; Liu, Z. Conformational stability and vibrational study of phenylacetyl chloride. J. Phys. Org. Chem. 2015, 28 (11), 703-711.
- Hesping, L.; Biswas, A.; Daniliuc, C. G.; Mück-Lichtenfeld, C.; Studer, A. Stereoselective Lewis base catalyzed formal 1,3-dipolar cycloaddition of azomethine imines with mixed anhydrides. Chem. Sci. 2015, 6 (2), 1252-1257.