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Thermo Scientific Chemicals
1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide, 97%
CAS: 1892-57-5 | C8H17N3 | 155.245 g/mol
化学物質識別子
CAS1892-57-5
IUPAC Name({[3-(dimethylamino)propyl]imino}methylidene)(ethyl)amine
Molecular FormulaC8H17N3
InChI KeyLMDZBCPBFSXMTL-UHFFFAOYSA-N
SMILESCCN=C=NCCCN(C)C
さらに表示
仕様
スペックシート
スペックシートFormLiquid
Refractive Index1.4590-1.4630 @ 20°C
Assay (GC)≥96.0%
Appearance (Color)Clear colorless to yellow
Identification (FTIR)Conforms
1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide is used as a carboxyl activating agent and activate phosphate groups in phospho mono and di esters. It is used in peptide synthesis, 3'-amino-3'-deoxyadenosine-5'-di- and triphosphates and in the preparation of antibodies like immunoconjugates. It plays a vital role for immobilization of large biomolecules in association with N-hydroxysuccinimide. It is also used in the acylation of phosphoranes.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide is used as a carboxyl activating agent and activate phosphate groups in phospho mono and di esters. It is used in peptide synthesis, 3′-amino-3′-deoxyadenosine-5′-di- and triphosphates and in the preparation of antibodies like immunoconjugates. It plays a vital role for immobilization of large biomolecules in association with N-hydroxysuccinimide. It is also used in the acylation of phosphoranes.
Solubility
Soluble in water.
Notes
Air sensitive. Incompatible with strong acids and strong oxidizing agents.
1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide is used as a carboxyl activating agent and activate phosphate groups in phospho mono and di esters. It is used in peptide synthesis, 3′-amino-3′-deoxyadenosine-5′-di- and triphosphates and in the preparation of antibodies like immunoconjugates. It plays a vital role for immobilization of large biomolecules in association with N-hydroxysuccinimide. It is also used in the acylation of phosphoranes.
Solubility
Soluble in water.
Notes
Air sensitive. Incompatible with strong acids and strong oxidizing agents.
RUO – Research Use Only
General References:
- Free base form of 'Water-soluble' carbodiimide. For applications see following entry. In the presence of CuCl2, (E)- or (Z)-2-substituted 3-hydroxy-3-phenylpropionate esters can be dehydrated stereoselectively to the corresponding (E) or (Z)-cinnamates: Tetrahedron Lett., 40, 5019 (1999).
- Li, J.; Yue, L.; Li, C.; Pan, Y.; Yang, L. Enantioselectivity and catalysis improvements of Pseudomonas cepacia lipase with Tyr and Asp modification. Catal. Sci. Technol. 2015, 5, 2681-2687.
- Lopez, R. J.; Babanova, S.; Artyushkova, K.; Atanassov, P. Surface modifications for enhanced enzyme immobilization and improved electron transfer of PQQ-dependent glucose dehydrogenase anodes. Bioelectrochemistry 2015, 105, 78-87.