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Citations & References (32)
Invitrogen™
BODIPY™ FL C5-Lactosylceramide complexed to BSA
緑色蛍光を示すBODIPY™ FL C5ラクトシルセアミドはBSAに複合体化されており、スフィンゴ脂質の輸送メカニズムおよび代謝メカニズムで使用できます。ウシ血清アルブミン（BSA）と蛍光脂質を複合体化することで、脂溶性プローブを溶解するための有機溶媒が不要になり、細胞標識が容易になります。BSA複合体化プローブは水に直接溶かすことができます詳細を見る
| 製品番号（カタログ番号） | 数量 |
|---|---|
| B34402 | 1 mg |
製品番号（カタログ番号） B34402
価格（JPY）お問い合わせください ›
50,800
線上優惠
Ends: 27-Mar-2026
84,800割引額 34,000 (40%)
Each
数量:
1 mg
緑色蛍光を示すBODIPY™ FL C5ラクトシルセアミドはBSAに複合体化されており、スフィンゴ脂質の輸送メカニズムおよび代謝メカニズムで使用できます。ウシ血清アルブミン（BSA）と蛍光脂質を複合体化することで、脂溶性プローブを溶解するための有機溶媒が不要になり、細胞標識が容易になります。BSA複合体化プローブは水に直接溶かすことができます。
研究用にのみ使用できます。診断用には使用いただけません。
仕様
化学物質名または材質Sphingolipids
励起／発光505/511 nm
推奨保存方法Store in freezer (-5°C to -30°C) and protect from light.
物理的フォームSolid
製品ラインBODIPY
数量1 mg
Unit SizeEach
引用および参考文献 (32)
引用および参考文献
Abstract
Inhibition of caveolar uptake, SV40 infection, and beta1-integrin signaling by a nonnatural glycosphingolipid stereoisomer.
Journal:J Cell Biol
PubMed ID:17371832
'Caveolar endocytosis is an important mechanism for the uptake of certain pathogens and toxins and also plays a role in the internalization of some plasma membrane (PM) lipids and proteins. However, the regulation of caveolar endocytosis is not well understood. We previously demonstrated that caveolar endocytosis and beta1-integrin signaling are
Regulation of caveolar endocytosis by syntaxin 6-dependent delivery of membrane components to the cell surface.
Journal:Nat Cell Biol
PubMed ID:16565709
'Caveolar endocytosis has an important function in the cellular uptake of some bacterial toxins, viruses and circulating proteins. However, the molecular machinery involved in regulating caveolar uptake is poorly defined. Here, we demonstrate that caveolar endocytosis is regulated by syntaxin 6, a target membrane soluble N-ethylmaleimide attachment protein receptor (t-SNARE)
Selective caveolin-1-dependent endocytosis of glycosphingolipids.
Journal:Mol Biol Cell
PubMed ID:12925761
'We studied the endocytosis of fluorescent glycosphingolipid (GSL) analogs in various cell types using pathway-specific inhibitors and colocalization studies with endocytic markers and DsRed caveolin-1 (cav-1). Based on inhibitor studies, all GSLs tested were internalized predominantly (>80%) by a clathrin-independent, caveolar-related mechanism, regardless of cell type. In addition, fluorescent lactosylceramide
A fluorescent glycolipid-binding peptide probe traces cholesterol dependent microdomain-derived trafficking pathways.
Journal:PLoS ONE
PubMed ID:18716682
'BACKGROUND: The uptake and intracellular trafficking of sphingolipids, which self-associate into plasma membrane microdomains, is associated with many pathological conditions, including viral and toxin infection, lipid storage disease, and neurodegenerative disease. However, the means available to label the trafficking pathways of sphingolipids in live cells are extremely limited. In order
Rab proteins mediate Golgi transport of caveola-internalized glycosphingolipids and correct lipid trafficking in Niemann-Pick C cells.
Journal:J Clin Invest
PubMed ID:12070301
'We recently showed that human skin fibroblasts internalize fluorescent analogues of the glycosphingolipids lactosylceramide and globoside almost exclusively by a clathrin-independent mechanism involving caveolae. In contrast, a sphingomyelin analogue is internalized approximately equally via clathrin-dependent and caveolar routes. Here, we further characterized the caveolar pathway for glycosphingolipids, showing that Golgi