BAPTA, AM, cell permeant chelator
BAPTA, AM, cell permeant chelator
Citations & References (662)
Invitrogen™

BAPTA, AM, cell permeant chelator

BAPTA、AMは細胞を透過させるキレート剤で、Mg2+を超えるCa2+に対して高い選択性を有しており、細胞内のCa2+のレベルを制御するために使用できます。BAPTAは、EDTAやEGTAよりもCa2+に対して選択的であり、金属結合もpHに対して感度が低くなります。詳細を見る
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製品番号（カタログ番号）数量
B676920 x 1mg
B120525mg
製品番号（カタログ番号） B6769
価格（JPY）
67,000
Each
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数量:
20 x 1mg
BAPTA、AMは細胞を透過させるキレート剤で、Mg2+を超えるCa2+に対して高い選択性を有しており、細胞内のCa2+のレベルを制御するために使用できます。BAPTAは、EDTAやEGTAよりもCa2+に対して選択的であり、金属結合もpHに対して感度が低くなります。
研究用にのみ使用できます。診断用には使用いただけません。
仕様
染色剤タイプキレート剤（非蛍光）
数量20 x 1mg
出荷条件室温
使用対象（アプリケーション）細胞の生存率と増殖
製品タイプ細胞の生存率と増殖
Unit SizeEach
組成および保存条件
フリーザー（-5℃～-30℃）に保存。

引用および参考文献 (662)

引用および参考文献
Abstract
Rescue of vasopressin V2 receptor mutants by chemical chaperones: specificity and mechanism.
Authors:Robben JH,Sze M,Knoers NV,Deen PM
Journal:Molecular biology of the cell
PubMed ID:16267275
Because missense mutations in genetic diseases of membrane proteins often result in endoplasmic reticulum (ER) retention of functional proteins, drug-induced rescue of their cell surface expression and understanding the underlying mechanism are of clinical value. To study this, we tested chemical chaperones and sarco(endo)plasmic reticulum Ca(2+) ATPase pump inhibitors on ... More
The small GTP-binding protein Rac promotes the dissociation of gelsolin from actin filaments in neutrophils.
Authors:Arcaro A
Journal:J Biol Chem
PubMed ID:9422735
Gelsolin is an actin filament-capping protein that has been shown to play a key role in cell migration. Here we have studied the involvement of phosphoinositide 3-kinase (PI 3-kinase) and GTP-binding proteins (G-proteins) in the regulation of gelsolin-actin interactions in neutrophils. Inhibition of PI 3-kinase activity in vivo by wortmannin ... More
Isoform-specific up-regulation by ouabain of Na+,K+-ATPase in cultured rat astrocytes.
Authors:Hosoi R, Matsuda T, Asano S, Nakamura H, Hashimoto H, Takuma K, Baba A
Journal:J Neurochem
PubMed ID:9349566
There are two alpha-subunit isoforms (alpha1 and alpha2) and two beta-subunit isoforms (beta1 and beta2) of Na+,K+-ATPase in astrocytes, but the functional heterodimer composition is not known. Ouabain (0.5-1.0 mM) increased the levels of alpha1 and beta1 mRNAs, whereas it decreased those of alpha2 and beta2 mRNAs in cultured rat ... More
Degradation of lamin B1 precedes oligonucleosomal DNA fragmentation in apoptotic thymocytes and isolated thymocyte nuclei.
Authors:Neamati N, Fernandez A, Wright S, Kiefer J, McConkey DJ
Journal:J Immunol
PubMed ID:7535814
Chromatin condensation and nuclear envelope breakdown are characteristic features of apoptotic cell death, but the mechanisms underlying these phenomena have not been identified. Solubilization of nuclear lamin is responsible for both events in mitosis. In this work, we report that glucocorticoids stimulate rapid degradation of lamin B1 that occurs before ... More
Calcineurin feedback inhibition of agonist-evoked cAMP formation.
Authors:Antoni FA, Barnard RJ, Shipston MJ, Smith SM, Simpson J, Paterson JM
Journal:J Biol Chem
PubMed ID:7499291
The effects of immunosuppressant blockers of calcineurin (protein phosphatase 2B) on cAMP formation and hormone release were investigated in mouse pituitary tumor (AtT20) cells. Immunosuppressants enhanced corticotropin-releasing factor- and isoproterenol-evoked cAMP production in proportion with their potency to block calcineurin. Further analysis of cAMP production revealed that intracellular Ca2+ derived ... More
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