Covalently dimerized SecA is functional in protein translocation.
Authors:de Keyzer J, van der Sluis EO, Spelbrink RE, Nijstad N, de Kruijff B, Nouwen N, van der Does C, Driessen AJ,
Journal:J Biol Chem
PubMed ID:16115882
'The ATPase SecA provides the driving force for the transport of secretory proteins across the cytoplasmic membrane of Escherichia coli. SecA exists as a dimer in solution, but the exact oligomeric state of SecA during membrane binding and preprotein translocation is a topic of debate. To study the requirements of ... More