CholEsteryl 4,4-Difluoro-5,7-Dimethyl-4-Bora-3a,4a-Diaza-s-Indacene-3-Dodecanoate (CholEsteryl BODIPY™ FL C12)
CholEsteryl 4,4-Difluoro-5,7-Dimethyl-4-Bora-3a,4a-Diaza-<i>s</i>-Indacene-3-Dodecanoate (CholEsteryl BODIPY&trade; FL C<sub>12</sub>)
Invitrogen™

CholEsteryl 4,4-Difluoro-5,7-Dimethyl-4-Bora-3a,4a-Diaza-s-Indacene-3-Dodecanoate (CholEsteryl BODIPY™ FL C12)

コレステロールエステルは、コレステロールの3β-水酸基に脂肪酸がエステル結合したものです。これらは非常に強い非極性を示す動物種で、アテローム性動脈硬化症プラークや低比重および高比重リポタンパク質(LDLおよびHDL)コアの主な脂質成分です。緑色蛍光BODIPY™ FL C12コレステロールエステルは、蛍光顕微鏡法によるリポタンパク質のコレステロール輸送および受容体媒介エンドサイトーシスのトレーサー詳細を見る
製品番号(カタログ番号)数量
C3927MP1 mg
製品番号(カタログ番号) C3927MP
価格(JPY)
43,600
キャンペーン価格
Ends: 27-Mar-2026
62,300
割引額 18,700 (30%)
Each
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数量:
1 mg
コレステロールエステルは、コレステロールの3β-水酸基に脂肪酸がエステル結合したものです。これらは非常に強い非極性を示す動物種で、アテローム性動脈硬化症プラークや低比重および高比重リポタンパク質(LDLおよびHDL)コアの主な脂質成分です。緑色蛍光BODIPY™ FL C12コレステロールエステルは、蛍光顕微鏡法によるリポタンパク質のコレステロール輸送および受容体媒介エンドサイトーシスのトレーサー、および非交換性の細胞膜マーカーとして使用できます。
研究用にのみ使用できます。診断用には使用いただけません。
仕様
化学物質名または材質Cholesterol Analogs
推奨保存方法Store in freezer (-5 to -30°C) and protect from light.
物理的フォームSolid
製品ラインBODIPY
数量1 mg
Unit SizeEach

よくあるご質問(FAQ)

How should I store CholEsteryl 4,4-Difluoro-5,7-Dimethyl-4-Bora-3a,4a-Diaza-s-Indacene-3-Dodecanoate (CholEsteryl BODIPY FL C12) (Cat. No. C3927MP) once reconstituted?

Once reconstituted in either chloroform or alcohol, store frozen, desiccated and protected from light. The CholEsteryl BODIPY FL C12 is not sensitive to changes in temperature (freeze/thaw), but the gradual accumulation of water from condensation and from the atmosphere will promote aggregation of the reagent over time.

Find additional tips, troubleshooting help, and resources within our Cell Imaging Support Center.

What is the molecular weight of CholEsteryl 4,4-Difluoro-5,7-Dimethyl-4-Bora-3a,4a-Diaza-s-Indacene-3-Dodecanoate (CholEsteryl BODIPY FL C12) (Cat. No. C3927MP)? Is the molecular weight based on the cholesteryl moiety together with BODIPY?

The molecular weight of the product is 786.98 g/mol. This is the molecular weight of the full molecule.

Find additional tips, troubleshooting help, and resources within our Cell Imaging Support Center.

How do I reconstitute CholEsteryl 4,4-Difluoro-5,7-Dimethyl-4-Bora-3a,4a-Diaza-s-Indacene-3-Dodecanoate (CholEsteryl BODIPY FL C12) (Cat. No. C3927MP)?

CholEsteryl BODIPY FL C12 is soluble up to 1 mM in chloroform. The molecular weight of this product is 786.98 g/mol. Additionally, there are references to the product being soluble up to 25 mM in ethanol and up to 0.5 mg/mL in methanol with sonication.

Find additional tips, troubleshooting help, and resources within our Cell Imaging Support Center.

引用および参考文献 (32)

引用および参考文献
Abstract
Streptococcal serum opacity factor increases the rate of hepatocyte uptake of human plasma high-density lipoprotein cholesterol.
Authors:Gillard BK, Rosales C, Pillai BK, Lin HY, Courtney HS, Pownall HJ,
Journal:Biochemistry
PubMed ID:20879789
Serum opacity factor (SOF), a virulence determinant of Streptococcus pyogenes, converts plasma high-density lipoproteins (HDL) to three distinct species: lipid-free apolipoprotein (apo) A-I, neo HDL, a small discoidal HDL-like particle, and a large cholesteryl ester-rich microemulsion (CERM) that contains the cholesterol esters (CE) of up to ~400000 HDL particles and ... More
Human granulosa cells use high density lipoprotein cholesterol for steroidogenesis.
Authors:Azhar S, Tsai L, Medicherla S, Chandrasekher Y, Giudice L, Reaven E
Journal:J Clin Endocrinol Metab
PubMed ID:9506760
This study examines the ability of human high density lipoproteins (HDL3) to deliver cholesteryl esters to human granulosa cells and describes the selective cholesterol pathway by which this occurs. Luteinized cells obtained from subjects undergoing in vitro fertilization-embryo transfer procedures were incubated with native HDL3 (or radiolabeled or fluorescently labeled ... More
High density lipoprotein (HDL) particle uptake mediated by scavenger receptor class B type 1 results in selective sorting of HDL cholesterol from protein and polarized cholesterol secretion.
Authors:Silver DL, Wang N, Xiao X, Tall AR
Journal:J Biol Chem
PubMed ID:11301333
'High density lipoprotein (HDL) mediates reverse transport of cholesterol from atheroma foam cells to the liver, but the mechanisms of hepatic uptake and trafficking of HDL particles are poorly understood. In contrast to its accepted role as a cell surface receptor, scavenger receptor class B type 1 (SR-BI) is shown ... More
Intracellular localization and metabolism of chylomicron remnants in the livers of low density lipoprotein receptor-deficient mice and apoE-deficient mice. Evidence for slow metabolism via an alternative apoE-dependent pathway.
Authors:Mortimer BC, Beveridge DJ, Martins IJ, Redgrave TG
Journal:J Biol Chem
PubMed ID:7499399
'The metabolism of chylomicron remnants in mice deficient in low density lipoprotein receptor (LDLr) or apolipoprotein E (apoE) was compared with that of control C57BL/6J mice. Mice were injected intravenously with chylomicron-like emulsions labeled with radioactive lipids. Blood samples were taken at fixed time intervals from the retro-orbital sinus, and ... More
Direct visualization of lipid deposition and reverse lipid transport in a perfused artery : roles of VLDL and HDL.
Authors:Rutledge JC, Mullick AE, Gardner G, Goldberg IJ
Journal:Circ Res
PubMed ID:10764410
'The major goal of this study was to determine the interactions of VLDL surface and core lipids with the artery wall. We first demonstrated in vitro that surface lipid in VLDL could be traced using the phospholipid-like fluorescent probe 1,1''-dioctadecyl-3,3, 3'',3''-tetramethyl-indocarbocyanine (DiI). The core of VLDL particles was traced by ... More