DQ™ Ovalbumin - Special Packaging

Citations & References (23)

Invitrogen™

DQ™ Ovalbumin - Special Packaging

DQオボアルブミンは、プロテアーゼ用の蛍光性基質です。タンパク質にBODIPY色素を強く標識すると、強い蛍光消光効果が現れます。プロテアーゼによって、DQオボアルブミンを単一の色素標識ペプチドに加水分解すると、この消光効果が緩和され、高輝度の蛍光産物を生成します。詳細を見る

製品番号（カタログ番号）	数量
D12053	5 x 1 mg

製品番号（カタログ番号） D12053

価格（JPY）

100,500

お問い合わせください ›

5 x 1 mg

DQオボアルブミンは、プロテアーゼ用の蛍光性基質です。タンパク質にBODIPY色素を強く標識すると、強い蛍光消光効果が現れます。プロテアーゼによって、DQオボアルブミンを単一の色素標識ペプチドに加水分解すると、この消光効果が緩和され、高輝度の蛍光産物を生成します。

研究用にのみ使用できます。診断用には使用いただけません。

標識または色素BODIPY™ FL

製品ラインDQ

製品タイプ抗原処理および抗原提示の研究

数量5 x 1 mg

出荷条件室温

基質プロテアーゼ基質

検出法蛍光

Substrate Propertiesタンパク質ベースの基質

Target Enzymeプロテアーゼ

Unit SizeEach

組成および保存条件

フリーザー（-5～-30度）に保存し、遮光してください。

よくあるご質問（FAQ）

Do you have an alternative for DQ Ovalbumin – Special Packaging (Cat. No. D12053) that can be purchased in the EU?

Unfortunately, DQ Ovalbumin – Special Packaging (Cat. No. D12053) is suspended for sale in the EU until further notice and there is no alternative for this product currently.

Find additional tips, troubleshooting help, and resources within our Cell Analysis Support Center.

引用および参考文献 (23)

引用および参考文献

Abstract

TLR9 signals after translocating from the ER to CpG DNA in the lysosome.

Authors:Latz E, Schoenemeyer A, Visintin A, Fitzgerald KA, Monks BG, Knetter CF, Lien E, Nilsen NJ, Espevik T, Golenbock DT

Journal:Nat Immunol

PubMed ID:14716310

'Microbial DNA sequences containing unmethylated CpG dinucleotides activate Toll-like receptor 9 (TLR9). We have found that TLR9 is localized to the endoplasmic reticulum (ER) of dendritic cells (DCs) and macrophages. Because there is no precedent for immune receptor signaling in the ER, we investigated how TLR9 is activated. We show ... More

Carbohydrate oxidation acidifies endosomes, regulating antigen processing and TLR9 signaling.

Authors:Lewis CJ, Cobb BA,

Journal:J Immunol

PubMed ID:20200279

'Phagocytes kill encapsulated microbes through oxidative cleavage of surface carbohydrates, releasing glycan fragments and microbial contents that serve as ligands for immune receptors, which tailor the immune response against the offending pathogen. The glycan fragments serve as MHC class II (MHC II) ligands and innate receptor agonists, whereas microbial proteins ... More

Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization.

Authors:Hornung V, Bauernfeind F, Halle A, Samstad EO, Kono H, Rock KL, Fitzgerald KA, Latz E,

Journal:Nat Immunol

PubMed ID:18604214

'Inhalation of silica crystals causes inflammation in the alveolar space. Prolonged exposure to silica can lead to the development of silicosis, an irreversible, fibrotic pulmonary disease. The mechanisms by which silica and other crystals activate immune cells are not well understood. Here we demonstrate that silica and aluminum salt crystals ... More

Digestion assays in allergenicity assessment of transgenic proteins.

Authors:Herman RA, Storer NP, Gao Y,

Journal:Environ Health Perspect

PubMed ID:16882518

'The food-allergy risk assessment for transgenic proteins expressed in crops is currently based on a weight-of-evidence approach that holistically considers multiple lines of evidence. This approach recognizes that no single test or property is known to distinguish allergens from nonallergens. The stability of a protein to digestion, as predicted by ... More

Loss-of-function mutations in Rab escort protein 1 (REP-1) affect intracellular transport in fibroblasts and monocytes of choroideremia patients.

Authors:Strunnikova NV, Barb J, Sergeev YV, Thiagarajasubramanian A, Silvin C, Munson PJ, Macdonald IM,

Journal:PLoS One

PubMed ID:20027300

'BACKGROUND: Choroideremia (CHM) is a progressive X-linked retinopathy caused by mutations in the CHM gene, which encodes Rab escort protein-1 (REP-1), an escort protein involved in the prenylation of Rabs. Under-prenylation of certain Rabs, as a result of loss of function mutations in REP-1, could affect vesicular trafficking, exocytosis and ... More

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