Search
Citations & References (31)
Invitrogen™
β-BODIPY™ FL C12-HPC (2-(4,4-Difluoro-5,7-Dimethyl-4-Bora-3a,4a-Diaza-s-Indacene-3-Dodecanoyl)-1-Hexadecanoyl-sn-Glycero-3-Phosphocholine)
強い蛍光を発するBODIPY®（4,4-ジフルオロ-3a,4a-ジアザ-s-インダセン）フルオロフォアは、他のほとんどの長波長色素とは異なり、本質的に脂溶性です。その結果、このフルオロフォアを組み込んだプローブは、天然脂質とよく似た特性を示す可能性が高くなります。BODIPY® 500/510ドデカン酸詳細を見る
| 製品番号（カタログ番号） | 数量 |
|---|---|
| D3792 | 100 μg |
製品番号（カタログ番号） D3792
価格（JPY）お問い合わせください ›
38,000
Each
数量:
100 μg
強い蛍光を発するBODIPY®（4,4-ジフルオロ-3a,4a-ジアザ-s-インダセン）フルオロフォアは、他のほとんどの長波長色素とは異なり、本質的に脂溶性です。その結果、このフルオロフォアを組み込んだプローブは、天然脂質とよく似た特性を示す可能性が高くなります。BODIPY® 500/510ドデカン酸（D-3823）やBODIPY FLドデカン酸（D-3822）などのBODIPY®脂肪酸アナログは、細胞内で天然様に輸送および代謝されます。したがって、これらは脂質輸送の効果的なトレーサーであり、汎用の膜プローブとしても有用です。
研究用にのみ使用できます。診断用には使用いただけません。
仕様
化学物質名または材質Phospholipids
推奨保存方法Store in freezer (-5 to -30°C) and protect from light.
物理的フォームSolid
製品ラインBODIPY
数量100 μg
Unit SizeEach
引用および参考文献 (31)
引用および参考文献
Abstract
Separation and characterization of late endosomal membrane domains.
Journal:J Biol Chem
PubMed ID:12065580
'Very little is known about the biophysical properties and the lipid or protein composition of membrane domains presumably present in endocytic and biosynthetic organelles. Here we analyzed the membrane composition of late endosomes by suborganellar fractionation in the absence of detergent. We found that the internal membranes of this multivesicular
Multidrug transporter activity in lymphocytes.
Journal:Br J Pharmacol
PubMed ID:15492020
'Multidrug transporters play a dual role in haematopoietic cells, mediating the efflux of xenobiotics and regulating cell migration. For several reasons including the lack of specific antibodies, reports of multidrug transporter distribution on lymphocytes conflict. Murine B cells have been reported to completely lack transporter activity. Through analysis of parental
gamma-cyclodextrins greatly enhance translocation of hydrophobic fluorescent phospholipids from vesicles to cells in culture. Importance of molecular hydrophobicity in phospholipid trafficking studies.
Journal:J Biol Chem
PubMed ID:10585403
'Short-chain, fluorescent derivatives are commonly used to investigate intracellular phospholipid trafficking. However, their use can yield misleading results because they, unlike the native species, can rapidly distribute between organelles due to their low hydrophobicity. On the other hand, hydrophobic derivatives are very difficult to introduce to cells and thus have
Fluorescent membrane probes incorporating dipyrrometheneboron difluoride fluorophores.
Journal:Anal Biochem
PubMed ID:1799206
'The spectroscopic properties of a new series of fatty acid analogs in which a dipyrrometheneboron difluoride fluorophore forms a segment of the acyl methylene chain are presented and their characteristics as fluorescent membrane probes are examined. When incorporated as a low mole fraction component in model phospholipid membranes, the probes
Intracellular surfactant removal from phagocytized minerals: development of a fluorescent method using a BODIPY-labeled phospholipid.
Journal:Inhal Toxicol
PubMed ID:10880156
'Lung surfactant serves as a protective coating when adsorbed on particle surfaces, so its removal or rate of removal in vivo may affect expression of mineral cytotoxicity. Removal of phospholipid surfactant components from the surface of mineral particles ingested by alveolar macrophages (AM) was measured using fluorescence microscopy. Dipalmitoylphosphatidylcholine with