What is the LoD for the EnzChek Phospholipase A1 Assay Kit (Cat. No. E10219)?
The EnzChek Phospholipase A1 Assay Kit (Cat. No. E10219) can detect PLA1 at 0.04 U/mL or lower.
引用および参考文献 (3)
引用および参考文献
Abstract
Crystal structure of the predicted phospholipase LYPLAL1 reveals unexpected functional plasticity despite close relationship to acyl protein thioesterases.
Authors:Bürger M, Zimmermann TJ, Kondoh Y, Stege P, Watanabe N, Osada H, Waldmann H, Vetter IR,
Journal:J Lipid Res
PubMed ID:22052940
'Sequence homology indicates the existence of three human cytosolic acyl protein thioesterases, including APT1 that is known to depalmitoylate H- and N-Ras. One of them is the lysophospholipase-like 1 (LYPLAL1) protein that on the one hand is predicted to be closely related to APT1 but on the other hand might ... More
Furin Is the Primary in Vivo Convertase of Angiopoietin-like 3 and Endothelial Lipase in Hepatocytes.
Authors:Essalmani R, Susan-Resiga D, Chamberland A, Asselin MC, Canuel M, Constam D, Creemers JW, Day R, Gauthier D, Prat A, Seidah NG,
Journal:
PubMed ID:23918928
'The proprotein convertases (PCs) furin, PC5/6, and PACE4 exhibit unique and/or complementary functions. Their knock-out (KO) in mice resulted in strong and specific phenotypes demonstrating that, in vivo, these PCs are unique and essential during development. However, they also exhibit redundant functions. Liver angiopoietin-like 3 (ANGPTL3) inhibits lipolysis by binding ... More
Measurement of the phospholipase activity of endothelial lipase in mouse plasma.
Authors:Basu D, Lei X, Josekutty J, Hussain MM, Jin W,
Journal:J Lipid Res
PubMed ID:23103358
Endothelial lipase (EL) is a major negative regulator of plasma HDL levels in mice, rabbits, and most probably, humans. Although this regulatory function is critically dependent on EL's hydrolysis of HDL phospholipids, as yet there is no phospholipase assay specific for EL in plasma. We developed such an assay for ... More