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Citations & References (38)
Invitrogen™
Fluorescein-5-(and-6)-Sulfonic Acid, Trisodium Salt
細胞不透過 性フルオレセイン-5-（および-6-）スルホン酸は、固定不可能な極性トレーサーとして使用して、融合、溶解、およびギャップ結合伝達を調べることができます。詳細を見る
| 製品番号（カタログ番号） | 数量 |
|---|---|
| F1130 | 100 mg |
製品番号（カタログ番号） F1130
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32,100
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Ends: 27-Mar-2026
53,600割引額 21,500 (40%)
Each
数量:
100 mg
細胞不透過 性フルオレセイン-5-（および-6-）スルホン酸は、固定不可能な極性トレーサーとして使用して、融合、溶解、およびギャップ結合伝達を調べることができます。
研究用にのみ使用できます。診断用には使用いただけません。
仕様
検出法蛍光
使用対象 (装置)蛍光顕微鏡
分子式C20H9Na3O8S
数量100 mg
推奨保存方法室温で保存し、光から保護します。
出荷条件室温
細胞内局在細胞膜&脂質
色Green
物理的フォームSolid
製品タイプ三ナトリウム塩
Unit SizeEach
引用および参考文献 (38)
引用および参考文献
Abstract
Rapid development of vasopressin-induced hydroosmosis in kidney collecting tubules measured by a new fluorescence technique.
Journal:Biophys J
PubMed ID:3224145
'The pre-steady-state kinetics of the vasopressin-induced increase in collecting tubule osmotic water permeability (Pf) has been measured by a new fluorescence technique. Isolated cortical collecting tubules (CCT) from rabbit kidney were perfused with physiological buffers containing the impermeant fluorophores fluorescein sulfonate (FS) and pyrenetetrasulfonic acid (PTSA). Tubules were subject to
The delta-isoform of protein kinase C causes inducible nitric-oxide synthase and nitric oxide up-regulation: key mechanism for oxidant-induced carbonylation, nitration, and disassembly of the microtubule cytoskeleton and hyperpermeability of barrier of intestinal epithelia.
Journal:J Pharmacol Exp Ther
PubMed ID:12606598
'Using intestinal (Caco-2) cells, we found that oxidant-induced disruption of barrier integrity requires microtubule disassembly. Protein kinase C (PKC)-delta isoform seems to be essential for disruption, but the mechanism is unknown. Because inducible nitric-oxide synthase (iNOS) is key to oxidant stress, we hypothesized that PKC-delta activation is essential in oxidant-induced
Phospholipase C-gamma inhibition prevents EGF protection of intestinal cytoskeleton and barrier against oxidants.
Journal:Am J Physiol Gastrointest Liver Physiol
PubMed ID:11447022
'Loss of intestinal barrier integrity is associated with oxidative inflammatory GI disorders including inflammatory bowel disease. Using monolayers of human intestinal epithelial (Caco-2) cells, we recently reported that epidermal growth factor (EGF) protects barrier integrity against oxidants by stabilizing the microtubule cytoskeleton, but the mechanism downstream of the EGF receptor
Activation of delta-isoform of protein kinase C is required for oxidant-induced disruption of both the microtubule cytoskeleton and permeability barrier of intestinal epithelia.
Journal:J Pharmacol Exp Ther
PubMed ID:12235228
'Using monolayers of intestinal (Caco-2) cells, we showed that oxidants disassemble the microtubule cytoskeleton and disrupt barrier integrity (permeability) (Banan et al., 2000a). Because exposure of our parental cells to oxidants causes protein kinase C (PKC)-delta to be translocated to particulate fractions, we hypothesized that PKC-delta activation is required for
Transepithelial water permeability in microperfused distal airways. Evidence for channel-mediated water transport.
Journal:J Clin Invest
PubMed ID:8609221
'Water movement across the airway epithelium is important for regulation of the volume and composition of airspace fluid. A novel approach is reported here to measure osmotic and diffusional water permeability in intact airways. Small airways (100-200 microns diameter, 1-2 mm length) from guinea pig lung were microdissected and perfused