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Fura-2、AM—は、レシオメトリックでUV光励起可能な高親和性の細胞内カルシウム指示薬です。このアセトキシメチル（AM）エステルは非侵襲的な細胞内取り込みに有用で、1 mgの容量（F-1201）およびDMSO溶液（F-1225）でもご用意しています。細胞不透過性ペンタカリウム（F-1200）およびペンタナトリウム（F-6799）塩形態の色素をご用意しています。
研究用にのみ使用できます。診断用には使用いただけません。
仕様
検出法蛍光
染色剤タイプ蛍光色素ベース
数量1mg
出荷条件室温
使用対象（アプリケーション）細胞生存率、増殖、細胞イメージング
使用対象 (装置)蛍光顕微鏡
製品タイプカルシウムインジケーター
Unit SizeEach
組成および保存条件
フリーザー（-5℃～-30℃）に保存し、遮光してください。
引用および参考文献 (4365)
引用および参考文献
Abstract
Mechanisms of photoswitch conjugation and light activation of an ionotropic glutamate receptor.
Journal:Proceedings of the National Academy of Sciences of the United States of America
PubMed ID:17578923
The analysis of cell signaling requires the rapid and selective manipulation of protein function. We have synthesized photoswitches that covalently modify target proteins and reversibly present and withdraw a ligand from its binding site due to photoisomerization of an azobenzene linker. We describe here the properties of a glutamate photoswitch
Simultaneous measurement of intracellular pH and Ca2+ in insulin-secreting cells by spectral imaging microscopy.
Journal:The American journal of physiology
PubMed ID:8967445
Functional implications of calcium permeability of the channel formed by pannexin 1.
Journal:The Journal of cell biology
PubMed ID:16908669
Although human pannexins (PanX) are homologous to gap junction molecules, their physiological function in vertebrates remains poorly understood. Our results demonstrate that overexpression of PanX1 results in the formation of Ca(2+)-permeable gap junction channels between adjacent cells, thus, allowing direct intercellular Ca(2+) diffusion and facilitating intercellular Ca(2+) wave propagation. More
Rescue of vasopressin V2 receptor mutants by chemical chaperones: specificity and mechanism.
Journal:Molecular biology of the cell
PubMed ID:16267275
Because missense mutations in genetic diseases of membrane proteins often result in endoplasmic reticulum (ER) retention of functional proteins, drug-induced rescue of their cell surface expression and understanding the underlying mechanism are of clinical value. To study this, we tested chemical chaperones and sarco(endo)plasmic reticulum Ca(2+) ATPase pump inhibitors on
Disruption of a single copy of the SERCA2 gene results in altered Ca2+ homeostasis and cardiomyocyte function.
Journal:The Journal of biological chemistry
PubMed ID:10970890