2,2-Difluorocyclopropanecarboxylic acid, 95%

Name: 2,2-Difluorocyclopropanecarboxylic acid, 95%
SKU: H25752.03

CAS: 107873-03-0 | C4H4F2O2 | 122.071 g/mol

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数量:

1 g

5 g

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製品番号（カタログ番号） H25752.03

または、製品番号H25752-03

価格（JPY）

数量:

1 g

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化学物質識別子

CAS107873-03-0

IUPAC Name2,2-difluorocyclopropane-1-carboxylic acid

Molecular FormulaC4H4F2O2

InChI KeyKMLMOVWSQPHQME-UHFFFAOYNA-N

SMILESOC(=O)C1CC1(F)F

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仕様

スペックシート

Appearance (Color)White to very pale brown

FormCrystals or powder or crystalline powder

Assay (Aqueous acid-base Titration)≥94.0 to ≤106.0%

Assay (GC)≥94.0%

Melting Point (clear melt)59.0-65.0?C

2,2-Difluorocyclopropanecarboxylic acid derivative (i.e. 2,2-difluorocyclopropanecarbonyl chloride) is used in Friedel-Crafts reactions with various arenes to prepare aryl 2,2-difluorocyclopropyl ketones.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
2,2-Difluorocyclopropanecarboxylic acid derivative (i.e. 2,2-difluorocyclopropanecarbonyl chloride) is used in Friedel-Crafts reactions with various arenes to prepare aryl 2,2-difluorocyclopropyl ketones.

Solubility
Soluble in water.

Notes
Incompatible with strong oxidizing agents.

RUO – Research Use Only

General References:

Dolbier, W. R.; Cornett, E.; Martinez, H.; Xu, W. Friedel-Crafts Reactions of 2,2-Difluorocyclopropanecarbonyl Chloride: Unexpected Ring-Opening Chemistry. J. Org. Chem. 2011, 76 (9), 3450-3456.
Liu, C-H.; Wang, S-A.; Ruszczycky, M. W.; Chen, H.; Li, K.; Murakami, K.; Liu, H. Studies of 1-Amino-2,2-difluorocyclopropane-1-carboxylic Acid: Mechanism of Decomposition and Inhibition of 1-Aminocyclopropane-1-carboxylic Acid Deaminase. Org. Lett. 2015, 17 (13), 3342-3345.