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Thermo Scientific Chemicals
O-(7-Aza-1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate, 99%
CAS: 148893-10-1 | C10H15F6N6OP | 380.24 g/mol
化学物質識別子
CAS148893-10-1
IUPAC Name[(dimethylamino)({3H-[1,2,3]triazolo[4,5-b]pyridin-3-yloxy})methylidene]dimethylazanium; hexafluoro-λ⁵-phosphanuide
Molecular FormulaC10H15F6N6OP
InChI KeyJNWBBCNCSMBKNE-UHFFFAOYSA-N
SMILESF[P-](F)(F)(F)(F)F.CN(C)C(ON1N=NC2=CC=CN=C12)=[N+](C)C
さらに表示
仕様
スペックシート
スペックシートAppearance (Color)White
FormCrystals or powder or crystalline powder
Assay (HPLC)≥98.5%
Identification (FTIR)Conforms
O-(7-Aza-1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate is a coupling reagent and used as an additive in peptide synthesis., It is also involved efficiently to speed up the coupling process and reduces the loss of chiral integrity.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
O-(7-Aza-1H-benzotriazol-1-yl)-N,N,N′,N′-tetramethyluronium hexafluorophosphate is a coupling reagent and used as an additive in peptide synthesis., It is also involved efficiently to speed up the coupling process and reduces the loss of chiral integrity.
Solubility
Soluble in acetonitrile. Insoluble in water.
Notes
Moisture sensitive. Incompatible with oxidizing agents and highly acidic or alkaline materials.
O-(7-Aza-1H-benzotriazol-1-yl)-N,N,N′,N′-tetramethyluronium hexafluorophosphate is a coupling reagent and used as an additive in peptide synthesis., It is also involved efficiently to speed up the coupling process and reduces the loss of chiral integrity.
Solubility
Soluble in acetonitrile. Insoluble in water.
Notes
Moisture sensitive. Incompatible with oxidizing agents and highly acidic or alkaline materials.
RUO – Research Use Only
General References:
- Yoshida, M.; Sasahara, K. I.; Doi, T. Total synthesis of cyclodepsipeptide spiruchostatin A on silyl-linked polymer-support. Tetrahedron 2015, 71 (40), 7647-7653.
- Xie, Y.; Yu, C.; Li, T.; Tu, S.; Yao, C. An NHC-Catalyzed In Situ Activation Strategy to β-Functionalize Saturated Carboxylic Acid: An Enantioselective Formal [3+ 2] Annulation for Spirocyclic Oxindolo-γ-butyrolactones. Chem. Eur. J. 2015, 21 (14), 5355-5359.