HCS CellMask™ Stains

Identify entire cells (cytoplasm and nucleus) during high-content screening (HCS) assays with the versatile HCS CellMask Red, CellMask Orange, CellMask Green, CellMask Blue, CellMask Deep Red, and CellMask Near-IR stains, which are fluorophores that can be used immediately after fixation and permeabilization, or after antibody labeling. They are available in a variety of colors for multiplexing protocols.

The versatile HCS CellMask Red, CellMask Orange, CellMask Green, CellMask Blue, CellMask Deep Red, and CellMask Near-IR stains are cell delineation tools for high content screening (HCS) platforms, label the entire cell (cytoplasm and nucleus) and provide an accurate backdrop against which the features of interest can be assessed. The HCS CellMask Red and Blue stains replace the HCS CellMask Red cytoplasmic/nuclear (Cat. No. H32711) and HCS CellMask Blue cytoplasmic/nuclear stains (Cat. No. H34558), respectively.

HCS CellMask stains can be applied to cells immediately after fixation or in the last step of multiplexing protocols, and they are compatible with detergent-based cell permeabilization protocols. If only nuclear staining is desired, HCS NuclearMask stains can be used for measuring DNA content in addition to enabling robust cell demarcation. HCS NuclearMask stains are also available in a choice of colors for multiplexing flexibility.