trans-4-Amino-N-Boc-L-proline methyl ester hydrochloride acts as a pharmaceutical intermediate. It is used to prepare N-Boc-protected proline methyl ester of calix[4]arene, which is efficiently catalyzes the enantioselective aldol reaction.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
trans-4-Amino-N-Boc-L-proline methyl ester hydrochloride acts as a pharmaceutical intermediate. It is used to prepare N-Boc-protected proline methyl ester of calix[4]arene, which is efficiently catalyzes the enantioselective aldol reaction.
Notes
Store in a cool place. Moisture sensitive. Incompatible with oxidizing agents and acids.
RUO – Research Use Only
Hahnenkamp, A.; Schäfers, M.; Bremer, C.; Höltke, C. Design and synthesis of small-molecule fluorescent photoprobes targeted to aminopeptdase N (APN/CD13) for optical imaging of angiogenesis. Bioconjugate Chem. 2013, 27 (6), 1027-1038.