(S)-2-Aminomethyl-1-Boc-pyrrolidine acts as an intermediate in organic synthesis. It is also used as a chiral and heterocyclic building block in synthetic chemistry.
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Applications
(S)-2-Aminomethyl-1-Boc-pyrrolidine acts as an intermediate in organic synthesis. It is also used as a chiral and heterocyclic building block in synthetic chemistry.
Solubility
Miscible with N-methylpyrrolidinone.
Notes
Air and moisture sensitive. Store in a cool place. Incompatible with oxidizing agents, strong acids and bases.
RUO – Research Use Only
General References:
- Patwardhan, N. N.; Morris, E. A.; Kharel, Y.; Raje, M. R.; Gao, M.; Tomsig, J. L.; Lynch, K. R.; Santos, W. L. Structure-Activity Relationship Studies and in Vivo Activity of Guanidine-Based Sphingosine Kinase Inhibitors: Discovery of SphK1- and SphK2-Selective Inhibitors. J. Med. Chem. 2015, 58 (4), 1879-1899.
- Morris, L. C.; Nance, K. D.; Gentry, P. R.; Days, E. L.; Weaver, C. D.; Niswender, C. M.; Thompson, A. D.; Jones, C. K.; Locuson, C. W.; Morrison, R. D.; Daniels, J. S.; Niswender, K. D.; Lindsley, C. W. Discovery of (S)-2-Cyclopentyl-N-((1-isopropylpyrrolidin2-yl)-9-methyl-1-oxo-2,9-dihydro-1H-pyrrido[3,4-b]indole-4-carboxamide (VU0453379): A Novel, CNS Penetrant Glucagon-Like Peptide 1 Receptor (GLP-1R) Positive Allosteric Modulator (PAM). J. Med. Chem. 2014, 57 (23), 10192-10197.